Nonpharmacologic Strategies for Managing Common Chemotherapy Adverse Effects: A Systematic Review

被引:113
作者
Lotfi-Jam, Kerryann
Carey, Mariko
Jefford, Michael
Schofield, Penelope
Charleson, Catherine
Aranda, Sanchia [1 ]
机构
[1] Peter MacCallum Canc Ctr, Dept Nursing & Support Care Res, Melbourne, Vic 8006, Australia
关键词
D O I
10.1200/JCO.2007.15.9053
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose Adverse effects of chemotherapy can be severe and can have a significant impact on a person's quality of life. With chemotherapy treatment increasingly administered in the ambulatory setting, there is a need for patients to be informed about effective self-care strategies to manage treatment adverse effects. Advice for patients needs to be based on evidence. This systematic review provides an overview of the intervention research in this area as well as an effectiveness review of nonpharmacologic (self-care) strategies evaluated in high-quality randomized controlled trials (RCTs). Methods An extensive literature search was conducted to identify RCTs relating to self-care strategies for reducing nausea/vomiting, constipation, diarrhea, fatigue, hair loss, or mucositis. Relevant studies published in peer-reviewed journals between 1980 and August 2007 were included. Study characteristics, results and methodologic quality were examined. High-quality RCTs were further analyzed to establish the effectiveness of specific self-care strategies. Results The search identified 77 RCTs. Findings from RCTs of reasonable quality provide limited support for cognitive distraction, exercise, hypnosis, relaxation, and systematic desensitization to reduce nausea and vomiting, psycho-education for fatigue, and scalp cooling to reduce hair loss. Conclusion Although some strategies seem promising, the quality of the RCTs was generally quite low, making it difficult to draw conclusions about the effectiveness of self-care strategies. Future studies require better design and reporting of methodologic issues to establish evidence-based self-care recommendations for people receiving chemotherapy.
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收藏
页码:5618 / 5629
页数:12
相关论文
共 104 条
[1]  
ARAKAWA S, 1995, CANCER NURS, V18, P60
[2]   Relaxation to reduce nausea, vomiting, and anxiety induced by chemotherapy in Japanese patients [J].
Arakawa, S .
CANCER NURSING, 1997, 20 (05) :342-349
[3]   Mapping the quality of life and unmet needs of urban women with metastatic breast cancer [J].
Aranda, S ;
Schofield, P ;
Weih, L ;
Yates, P ;
Milne, D ;
Faulkner, R ;
Voudouris, N .
EUROPEAN JOURNAL OF CANCER CARE, 2005, 14 (03) :211-222
[4]   Symptom experiences during chemotherapy treatment-With focus on nausea and vomiting [J].
Bergkvist, Karin ;
Wengstrom, Yvonne .
EUROPEAN JOURNAL OF ONCOLOGY NURSING, 2006, 10 (01) :21-29
[5]   Massage relieves nausea in women with breast cancer who are undergoing chemotherapy [J].
Billhult, Annika ;
Bergbom, Ingegerd ;
Stener-Victorin, Elisabet .
JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE, 2007, 13 (01) :53-57
[6]  
Buckingham R, 1997, Eur J Cancer Care (Engl), V6, P59, DOI 10.1111/j.1365-2354.1997.tb00270.x
[7]  
BURISH T G, 1981, Journal of Behavioral Medicine, V4, P65, DOI 10.1007/BF00844848
[8]   EFFECTIVENESS OF BIOFEEDBACK AND RELAXATION TRAINING IN REDUCING THE SIDE-EFFECTS OF CANCER-CHEMOTHERAPY [J].
BURISH, TG ;
JENKINS, RA .
HEALTH PSYCHOLOGY, 1992, 11 (01) :17-23
[9]   PREPARING PATIENTS FOR CANCER-CHEMOTHERAPY - EFFECT OF COPING PREPARATION AND RELAXATION INTERVENTIONS [J].
BURISH, TG ;
SNYDER, SL ;
JENKINS, RA .
JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY, 1991, 59 (04) :518-525
[10]   CONDITIONED SIDE-EFFECTS INDUCED BY CANCER-CHEMOTHERAPY - PREVENTION THROUGH BEHAVIORAL TREATMENT [J].
BURISH, TG ;
CAREY, MP ;
KROZELY, MG ;
GRECO, FA .
JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY, 1987, 55 (01) :42-48