Emergence of Different Recombinant Porcine Reproductive and Respiratory Syndrome Viruses, China

被引：29

作者：

Liu, Yanyan ^{[1
,2
,4
]}

Li, Jianda ^{[1
]}

Yang, Jie ^{[1
]}

Zeng, Hao ^{[1
]}

Guo, Lihui ^{[1
]}

Ren, Sufang ^{[1
]}

Sun, Wenbo ^{[1
]}

Chen, Zhi ^{[1
]}

Cong, Xiaoyan ^{[1
]}

Shi, Jianli ^{[1
]}

Chen, Lei ^{[1
]}

Du Yijun ^{[1
,3
]}

Li, Jun ^{[1
,3
]}

Wang, Jinbao ^{[1
,2
,3
]}

Wu, Jiaqiang ^{[1
,2
,3
]}

Yu, Jiang ^{[1
]}

机构：

[1] Shandong Acad Agr Sci, Inst Anim Sci & Vet Med, Shandong Key Lab Anim Dis Control & Breeding, Jinan 250100, Shandong, Peoples R China

[2] Shandong Univ, Sch Life Sci, Jinan 250100, Shandong, Peoples R China

[3] Shandong Normal Univ, Sch Life Sci, Jinan 250014, Shandong, Peoples R China

[4] Shandong Acad Agr Sci, Biotechnol Res Ctr, Jinan 250100, Shandong, Peoples R China

来源：

SCIENTIFIC REPORTS | 2018年 / 8卷

关键词：

NORTH-AMERICAN; NADC30-LIKE STRAIN; MOSAIC STRUCTURE; PRRSV; ISOLATE; TYPE-1; IDENTIFICATION; PATHOGENICITY; REPLICATION; VIRULENCE;

D O I：

10.1038/s41598-018-22494-4

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Epidemiological investigations were conducted on recently emerging porcine reproductive and respiratory syndrome virus (PRRSV) strains in Shandong province in 2014-2015. The proportion of the NADC30 strain identified by ORF7 sequence alignment has been gradually increasing. Three emerging PRRSV strains were successfully isolated, and the complete genomic sequences were determined. Our results indicate the importance of recombinant strains in Shandong province, China. There was a varied degree of recombination of two or three strains (classical, HP-PRRSV and/or NADC30). Moreover, the recombination strains affected the pathogenicity of newly emerged strains.

引用

页数：15

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