A Single Immunization With Optimized DNA Vaccines Protects Against Lethal Ebola Virus Challenge in Mice and Induces Seroconversion in Non-Human Primates Following a DNA Prime-DNA Boost Approach

被引:0
|
作者
Patel, Ami [1 ]
Reuschel, Emma L. [1 ]
Scott, Veronica L. [1 ]
Kraynyak, Kimberly A.
Wong, Gary [2 ]
Villarreal, Daniel O. [1 ]
Karuppiah, Muthumani [1 ]
Shedlock, Devon [1 ]
Yan, Jian
Broderick, Kate E.
Khan, Amir
Tierney, Kevin [2 ]
Kobinger, Gary P. [1 ,2 ,3 ]
Sardesai, Niranjan
Weiner, David B. [1 ]
机构
[1] Univ Penn, Philadelphia, PA 19104 USA
[2] Publ Hlth Agcy Canada, Winnipeg, MB, Canada
[3] Univ Manitoba, Winnipeg, MB, Canada
关键词
D O I
10.1016/S1525-0016(16)34059-X
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
450
引用
收藏
页码:S178 / S179
页数:2
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