Perfluorinated Compounds and Total and Extractable Organic Fluorine in Human Blood Samples from China

被引：159

作者：

Yeung, Leo W. Y. ^{[2
]}

Miyake, Yuichi ^{[1
]}

Taniyasu, Sachi ^{[1
]}

Wang, Yuan ^{[2
]}

Yu, Hongxia ^{[3
]}

So, M. K. ^{[2
]}

Jiang, Guibin ^{[4
]}

Wu, Yongning ^{[5
]}

Li, Jingguang ^{[5
]}

Giesy, John P. ^{[2
,3
,6
,7
,8
,9
]}

Yamashita, Nobuyosh ^{[1
]}

Lam, Paul K. S. ^{[2
]}

机构：

[1] Natl Inst Adv Ind Sci & Technol, Tsukuba, Ibaraki 3058569, Japan

[2] City Univ Hong Kong, Ctr Coastal Pollut & Conservat, Dept Biol & Chem, Kowloon, Hong Kong, Peoples R China

[3] Nanjing Univ, Sch Environm, State Key Lab Pollut Control & Resources, Nanjing 210093, Peoples R China

[4] Chinese Acad Sci, Ecoenvironm Sci Res Ctr, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China

[5] Ctr Dis Control & Prevent, Beijing 100050, Peoples R China

[6] Univ Saskatchewan, Dept Vet Biomed Sci, Saskatoon, SK, Canada

[7] Univ Saskatchewan, Toxicol Ctr, Saskatoon, SK, Canada

[8] Michigan State Univ, Dept Zool, Natl Food Safety & Toxicol Ctr, E Lansing, MI 48824 USA

[9] Michigan State Univ, Ctr Integrat Toxicol, E Lansing, MI 48824 USA

来源：

ENVIRONMENTAL SCIENCE & TECHNOLOGY | 2008年 / 42卷 / 21期

关键词：

D O I：

10.1021/es800631n

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

An improved extraction (ion pairing) and cleanup (ENVI-carb and solid phase extraction) method was developed for analysis of perfluorinated compounds (PFCs) in human whole blood samples from China. Ten PFCs including PFOS, PFHxS, PFOSA, PFDoDA, PFUnDA, PFDA, PFNA, PFOA, PFHpA, and PFHxA were detected in the blood samples (n = 30) from five cities (Jintan, Nanjing, Guiyang, Beijing, and Shenyang). PFOS was found to be the dominant PFC ranging from 0.446-83.1 ng/mL. Total fluorine (TF) and extractable organic fluorine (EOF) also were measured in the blood samples using combustion ion chromatography for fluorine. Analysis of known PFCs and extractable organic fluorine showed that known PFCs could account for >70% of EOF in samples from Beijing, Shenyang, and Guiyang, whereas known PFCs could only account for similar to 30% of EOF in samples from Jintan. Results of the present study indicated the presence of substantial amounts of unidentified organic fluorine in human blood samples from Jintan. Characterization and identification of these unidentified fluorinated compounds will be instructive.

引用

页码：8140 / 8145

页数：6

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