U2

被引：2

作者：

Alam, SL ^{[1
]}

Sundquist, WI ^{[1
]}

机构：

[1] Univ Utah, Dept Biochem, Salt Lake City, UT 84112 USA

来源：

NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2006年 / 13卷 / 03期

关键词：

D O I：

10.1038/nsmb0306-186

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two new crystal structures of ubiquitin ( Ub) in complex with fragments of the endosomal proteins Rabex-5 and HRS show intriguing new modes of Ub binding and reveal that both fragments can bind two Ub molecules simultaneously.

引用

页码：186 / 188

页数：3

共 28 条

[1] Structural basis for recognition of ubiquitinated cargo by Tom1-GAT domain [J].

Akutsu, M ;

Kawasaki, M ;

Katoh, Y ;

Shiba, T ;

Yamaguchi, Y ;

Kato, R ;

Kato, K ;

Nakayama, K ;

Wakatsuki, S .

FEBS LETTERS, 2005, 579 (24) :5385-5391

[2] Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail [J].

Hamilton, KS ;

Ellison, MJ ;

Barber, KR ;

Williams, RS ;

Huzil, JT ;

McKenna, S ;

Ptak, C ;

Glover, M ;

Shaw, GS .

STRUCTURE, 2001, 9 (10) :897-904

[3] The ubiquitin system for protein degradation and some of its roles in the control of the cell division cycle [J].

Hershko, A .

CELL DEATH AND DIFFERENTIATION, 2005, 12 (09) :1191-1197

[4] Ubiquitin-binding domains [J].

Hicke, L ;

Schubert, HL ;

Hill, CP .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2005, 6 (08) :610-621

[5] Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins [J].

Hicke, L ;

Dunn, R .

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, 2003, 19 :141-172

[6] Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting [J].

Hirano, S ;

Kawasaki, M ;

Ura, H ;

Kato, R ;

Raiborg, C ;

Stenmark, H ;

Wakatsuki, S .

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2006, 13 (03) :272-277

[7] A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal protein degradation systems [J].

Hofmann, K ;

Falquet, L .

TRENDS IN BIOCHEMICAL SCIENCES, 2001, 26 (06) :347-350

[8] Solution structure of a CUE-ubiquitin complex reveals a conserved mode of ubiquitin binding [J].

Kang, RS ;

Daniels, CM ;

Francis, SA ;

Shih, SC ;

Salerno, WJ ;

Hicke, L ;

Radhakrishnan, I .

CELL, 2003, 113 (05) :621-630

[9] Receptor downregulation and multivesicular-body sorting [J].

Katzmann, DJ ;

Odorizzi, G ;

Emr, SD .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2002, 3 (12) :893-905

[10] Molecular mechanism of ubiquitin recognition by GGA3 GAT domain [J].

Kawasaki, M ;

Shiba, T ;

Shiba, Y ;

Yamaguchi, Y ;

Matsugaki, N ;

Igarashi, N ;

Suzuki, M ;

Kato, R ;

Kato, K ;

Nakayama, K ;

Wakatsuki, S .

GENES TO CELLS, 2005, 10 (07) :639-654

← 1 2 3 →