One-pot mechanosynthesis of aromatic amides and dipeptides from carboxylic acids and amines

被引：84
|
作者：
Strukil, Vjekoslav [1 ]
Bartolec, Boris [1 ]
Portada, Tomislav [1 ]
Dilovic, Ivica [2 ]
Halasz, Ivan [3 ]
Margetic, Davor [1 ]
机构：
[1] Rudjer Boskovic Inst, Div Organ Chem & Biochem, HR-10002 Zagreb, Croatia
[2] Univ Zagreb, Fac Sci, Dept Chem, Zagreb 41000, Croatia
[3] Rudjer Boskovic Inst, Div Chem Mat, HR-10002 Zagreb, Croatia
来源：
CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 99期
关键词：
ASYMMETRIC ALDOL REACTION; (S)-PROLINE-CONTAINING DIPEPTIDES; GREEN SYNTHESIS; BOND FORMATION; SOLID-STATE; ORGANOCATALYSTS; DIFFRACTION;
D O I：
10.1039/c2cc36613d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Environmentally friendly one-pot synthesis of amides, bis-amides and dipeptides by mechanochemical carbodiimide-mediated coupling of carboxylic acids and amines is described; high reaction yields and simple aqueous work-up allow for the clean, practical and fast preparation of a variety of compounds containing the amide bond from readily accessible reagents.
引用
收藏
页码：12100 / 12102
页数：3
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