Copper-catalyzed one-pot synthesis of 2H-1,4-benzoxazin-3-(4H)-ones from 2-(o-haloaryloxy) acyl chlorides and primary amines

被引：3

作者：

Hu, Qunxian ^{[1
]}

Xia, Ziming ^{[1
]}

Fan, Ling ^{[1
]}

Zheng, Jiening ^{[1
]}

Wang, Xiaoxia ^{[1
]}

Lv, Xin ^{[1
]}

机构：

[1] Zhejiang Normal Univ, Coll Chem & Life Sci, Zhejiang Key Lab React Chem Solid Surfaces, Jinhua 321004, Peoples R China

来源：

ARKIVOC | 2012年

关键词：

Copper-catalyzed; one-pot; C-N coupling; condensation; 2H-1,4-benzoxazin-3-(4H)-one; C-N; COUPLING REACTIONS; EFFICIENT; ANNULATION; SULFIDES;

D O I：

10.3998/ark.5550190.0013.612

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A facile and efficient Cu(I)-catalyzed one-pot synthesis of 2H-1,4-benzoxazin-3-(4H)-one derivatives has been developed. The condensation between 2-(o-haloaryloxy) acyl chlorides and primary amines followed by Cu(I)-catalyzed intramolecular C-N bond coupling afforded a variety of 2H-1,4-benzoxazin-3-(4H)-ones in good to excellent yields. Diversified substitutents on the 4-position could be conveniently introduced.

引用

页码：129 / 142

页数：14

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