The dynamic relationship between pain, depression and cognitive function in a sample of newly diagnosed arthritic adults: a cross-lagged panel model

被引:18
作者
James, Richard J. E. [1 ,2 ,3 ]
Ferguson, Eamonn [1 ,2 ]
机构
[1] Univ Nottingham, Sch Psychol, Univ Pk, Nottingham, England
[2] City Hosp, Acad Rheumatol, Arthrit UK Pain Ctr, Nottingham, England
[3] Univ Nottingham, NIHR Nottingham Biomed Res Ctr, Nottingham, England
关键词
Arthritis; cognitive function; depression; longitudinal; pain; OLDER-ADULTS; RECIPROCAL RELATIONSHIP; SOCIAL-ISOLATION; EPIDEMIOLOGY; METAANALYSIS; DISABILITY; HEALTH; ANXIETY; PEOPLE; RISK;
D O I
10.1017/S0033291719001673
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Background Pain and depression are common in the population and co-morbid with each other. Both are predictive of one another and are also associated with cognitive function; people who are in greater pain and more depressed respectively perform less well on tests of cognitive function. It has been argued that pain might cause deterioration in cognitive function, whereas better cognitive function earlier in life might be a protective factor against the emergence of disease. When looking at the dynamic relationship between these in chronic diseases, studying samples that already have advanced disease progression often confounds this relationship. Methods Using data from waves 1 to 3 of the English Longitudinal Study of Ageing (ELSA) (n= 516), we examined the interplay between pain, cognitive function and depression in a subsample of respondents reporting a diagnosis of arthritis at wave 2 of the ELSA using cross-lagged panel models. Results The models showed that pain, cognitive function and depression at wave 1, prior to diagnosis, predict pain at wave 2, and that pain at wave 1 predicts depression at wave 2. Pain and depression at wave 2 predict cognitive function at wave 3. Conclusions The results indicate that better cognitive function might be protective against the emergence of pain prior to an arthritis diagnosis, but cognitive function is subsequently impaired by pain and depression. Furthermore, higher depression predicts lower cognitive function, but not vice versa. This is discussed in the context of the emerging importance of inflammation in depression.
引用
收藏
页码:1663 / 1671
页数:9
相关论文
共 60 条
[1]   Epidemiology of adult rheumatoid arthritis [J].
Alamanos, Y ;
Drosos, AA .
AUTOIMMUNITY REVIEWS, 2005, 4 (03) :130-136
[2]   Arthritis and cognitive impairment in older adults [J].
Baker, Nancy A. ;
Barbour, Kamil E. ;
Helmick, Charles G. ;
Zack, Matthew ;
Al Snih, Soham .
RHEUMATOLOGY INTERNATIONAL, 2017, 37 (06) :955-961
[3]  
Banks J, 2011, LONGITUD LIFE COURSE, V2, P101, DOI 10.14301/llcs.v2i2.115
[4]   Evidence for working memory deficits in chronic pain: A systematic review and meta-analysis [J].
Berryman, Carolyn ;
Stanton, Tasha R. ;
Bowering, K. Jane ;
Tabor, Abby ;
McFarlane, Alexander ;
Moseley, G. Lorimer .
PAIN, 2013, 154 (08) :1181-1196
[5]   Quality of life among older people with poor functioning. The influence of perceived control over life [J].
Bowling, Ann ;
Seetai, Sharon ;
Morris, Richard ;
Ebrahim, Shah .
AGE AND AGEING, 2007, 36 (03) :310-315
[6]   Assessment of pain [J].
Breivik, H. ;
Borchgrevink, P. C. ;
Allen, S. M. ;
Rosseland, L. A. ;
Romundstad, L. ;
Hals, E. K. Breivik ;
Kvarstein, G. ;
Stubhaug, A. .
BRITISH JOURNAL OF ANAESTHESIA, 2008, 101 (01) :17-24
[7]   Persistent pain and depression: A biopsychosocial perspective [J].
Campbell, LC ;
Clauw, DJ ;
Keefe, FJ .
BIOLOGICAL PSYCHIATRY, 2003, 54 (03) :399-409
[8]   Longitudinal relationships between anxiety, depression, and pain: Results from a two-year cohort study of lower extremity trauma patients [J].
Castillo, Renan C. ;
Wegener, Stephen T. ;
Heins, Sara E. ;
Haythornthwaite, Jennifer A. ;
MacKenzie, Ellen J. ;
Bosse, Michael J. .
PAIN, 2013, 154 (12) :2860-2866
[9]   Reciprocal relationship between pain and depression in older adults: Evidence from the English Longitudinal Study of Ageing [J].
Chou, Kee-Lee .
JOURNAL OF AFFECTIVE DISORDERS, 2007, 102 (1-3) :115-123
[10]  
COSTA P T JR, 1987, American Journal of Cardiology, V60, p20J, DOI 10.1016/0002-9149(87)90679-5