A facile one pot synthesis of 2-aryl-4-[2H-2-oxo-[1]benzopyran-3-yl] 2,3-dihydro and 2,5-dihydro-1,5-benzothiazepines

被引：8
|
作者：
Rao, VR [1 ]
Reddy, MMM [1 ]
机构：
[1] Natl Inst Technol, Dept Chem, Warangal 506004, Andhra Pradesh, India
来源：
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2006年 / 181卷 / 02期
关键词：
3-acetylcoumarin; chalcone; benzothiazepine;
D O I：
10.1080/104265091001326
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
3-acetyl coumarins on condensation with various aromatic aldehydes in the presence of piperidine gave corresponding chalcones in a solid state under solvent free conditions. These chalcones are isolated and characterized. The in-situ-formed chalcones (1) are also converted into corresponding 2-aryl-4-[2H-2oxo[1]benzopyran-3-yl]-2,3-dihydro (3) and 2,5-dihydro-1,5-benzothiazepines (4) in one step by interacting with orthoamino thiophenol. Both the 2,3-dihydro (3) and 2,5-dihydrobenzothiazepines ( 4) have been converted into same tetrahydrobenzothiazepine (5). Finally, the tetrahydrobenzo thiazepine (5) is converted into its acetyl derivative (11). The structures of the title compounds have been confirmed on the basis of their microanalytical, IR, H-1 NMR, and mass spectral data.
引用
收藏
页码：461 / 471
页数：11
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