Structures and Biological Activities of Secondary Metabolites from Trichoderma harzianum

被引：28
|
作者：
Guo, Rui [1 ]
Li, Gang [1 ]
Zhang, Zhao [2 ]
Peng, Xiaoping [1 ]
机构：
[1] Qingdao Univ, Sch Pharm, Dept Nat Med Chem & Pharmacognosy, Qingdao 266071, Peoples R China
[2] Qingdao Univ, Affiliated Hosp, Dept Hand & Foot Surg, Qingdao 266003, Peoples R China
来源：
MARINE DRUGS | 2022年 / 20卷 / 11期
基金：
中国博士后科学基金; 中国国家自然科学基金;
关键词：
natural products; Trichoderma harzianum; marine sources; bioactivity; secondary metabolites; ANTIBIOTIC PEPTIDES; PHYSICOCHEMICAL PROPERTIES; FUNGAL METABOLITES; TRICHORZINS HA; SPONGE; FERMENTATION; ANTIFUNGAL; PEPTAIBOL; SEQUENCE; STRAINS;
D O I：
10.3390/md20110701
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The biocontrol fungus Trichoderma harzianum, from both marine and terrestrial environments, has attracted considerable attention. T. harzianum has a tremendous potential to produce a variety of bioactive secondary metabolites (SMs), which are an important source of new herbicides and antibiotics. This review prioritizes the SMs of T. harzianum from 1988 to June 2022, and their relevant biological activities. Marine-derived SMs, especially terpenoids, polyketides, and macrolides compounds, occupy a significant proportion of natural products from T. harzianum, deserving more of our attention.
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页数：17
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