Inflammatory dietary pattern and risk of depression among women

被引:143
作者
Lucas, Michel [1 ,2 ]
Chocano-Bedoya, Patricia [1 ]
Shulze, Mathias B. [3 ]
Mirzaei, Fariba [1 ]
O'Reilly, Eilis J. [1 ,4 ,5 ]
Okereke, Olivia I. [4 ,5 ,6 ,7 ]
Hu, Frank B. [1 ,4 ,5 ,6 ]
Willett, Walter C. [1 ,4 ,5 ,6 ]
Ascherio, Alberto [1 ,4 ,5 ,6 ]
机构
[1] Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA
[2] Univ Laval, Dept Social & Prevent Med, Quebec City, PQ G1V 2M2, Canada
[3] German Inst Human Nutr, Dept Mol Epidemiol, D-14558 Nuthetal, Germany
[4] Brigham & Womens Hosp, Channing Div Network Med, Boston, MA 02115 USA
[5] Harvard Univ, Sch Med, Boston, MA 02115 USA
[6] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA
[7] Brigham & Womens Hosp, Dept Psychiat, Boston, MA 02115 USA
基金
美国国家卫生研究院;
关键词
Depression; Inflammatory markers; C-reactive protein; Interleukin-6; Tumor necrosis factor alpha receptor 2; Diet pattern; Cohort; Reduced-rank regression; Women; C-REACTIVE PROTEIN; CARDIOVASCULAR-DISEASE; INCIDENT DEPRESSION; FATTY-ACIDS; MARKERS; SYMPTOMS; ASSOCIATION; CONSUMPTION; HEALTHY; REPRODUCIBILITY;
D O I
10.1016/j.bbi.2013.09.014
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Background: Inflammation is considered as a mechanism leading to depression, but the association between inflammatory dietary pattern and depression risk is unknown. Methods: Using reduced-rank regression, we identified a dietary pattern that was related to plasma levels of inflammatory markers (C-reactive protein, interleukin-6, tumor necrosis factor a receptor 2), and we conducted a prospective analysis of the relationship of this pattern and depression risk among participants in the Nurses' Health Study. A total of 43,685 women (aged 50-77) without depression at baseline (1996) were included and followed up until 2008. Diet information was obtained from food frequency questionnaires completed between 1984 through 2002 and computed as cumulative average of dietary intakes with a 2-year latency applied. We used a strict definition of depression that required both self-reported physician-diagnosed depression and use of antidepressants, and a broader definition that included women who reported either clinical diagnosis or antidepressant use. Results: During the 12-year follow-up, we documented 2594 incident cases of depression using the stricter definition and 6446 using the broader definition. After adjustment for body mass index and other potential confounders, relative risks comparing extreme quintiles of the inflammatory dietary pattern were 1.41 (95% confidence interval [CI], 1.22, 1.63; P-trend <.001) for the strict definition and 1.29 (95% CI, 1.18, 1.41; P-trend <.001) for the broader definition of depression. Conclusions: The inflammatory dietary pattern is associated with a higher depression risk. This finding suggests that chronic inflammation may underlie the association between diet and depression. (C) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码:46 / 53
页数:8
相关论文
共 55 条
[1]   Inflammation and cancer: How hot is the link? [J].
Aggarwal, Bharat B. ;
Shishodia, Shishir ;
Sandur, Santosh K. ;
Pandey, Manoj K. ;
Sethi, Gautam .
BIOCHEMICAL PHARMACOLOGY, 2006, 72 (11) :1605-1621
[2]   Dietary pattern and depressive symptoms in middle age [J].
Akbaraly, Tasnime N. ;
Brunner, Eric J. ;
Ferrie, Jane E. ;
Marmot, Michael G. ;
Kivimaki, Mika ;
Singh-Manoux, Archana .
BRITISH JOURNAL OF PSYCHIATRY, 2009, 195 (05) :408-413
[3]   Red Meat Intake Is Associated with Metabolic Syndrome and the Plasma C-Reactive Protein Concentration in Women [J].
Azadbakht, Leila ;
Esmaillzadeh, Ahmad .
JOURNAL OF NUTRITION, 2009, 139 (02) :335-339
[4]   Dietary factors that promote or retard inflammation [J].
Basu, A ;
Devaraj, S ;
Jialal, I .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2006, 26 (05) :995-1001
[5]  
Belmaker RH, 2008, NEW ENGL J MED, V358, P55, DOI [10.1056/NEJMra073096, 10.1038/nrdp.2016.65]
[6]   PERFORMANCE OF A 5-ITEM MENTAL-HEALTH SCREENING-TEST [J].
BERWICK, DM ;
MURPHY, JM ;
GOLDMAN, PA ;
WARE, JE ;
BARSKY, AJ ;
WEINSTEIN, MC .
MEDICAL CARE, 1991, 29 (02) :169-176
[7]   Omega-3 fatty acids for the treatment of depression: systematic review and meta-analysis [J].
Bloch, M. H. ;
Hannestad, J. .
MOLECULAR PSYCHIATRY, 2012, 17 (12) :1272-1282
[8]   Chronic inflammatory diseases are stimulated by current lifestyle: how diet, stress levels and medication prevent our body from recovering [J].
Bosma-den Boer, Margarethe M. ;
van Wetten, Marie-Louise ;
Pruimboom, Leo .
NUTRITION & METABOLISM, 2012, 9
[9]   Prospective study on long-term dietary patterns and incident depression in middle-aged and older women [J].
Chocano-Bedoya, Patricia O. ;
O'Reilly, Eilis J. ;
Lucas, Michel ;
Mirzaei, Fariba ;
Okereke, Olivia I. ;
Fung, Teresa T. ;
Hu, Frank B. ;
Ascherio, Alberto .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2013, 98 (03) :813-820
[10]   Antimicrobial, antioxidant and anti-inflammatory phenolic activities in extra virgin olive oil [J].
Cicerale, S. ;
Lucas, L. J. ;
Keast, R. S. J. .
CURRENT OPINION IN BIOTECHNOLOGY, 2012, 23 (02) :129-135