Functionalization of carbon nanotubes for biocompatibility and biomolecular recognition

被引：735

作者：

Shim, M ^{[1
]}

Kam, NWS ^{[1
]}

Chen, RJ ^{[1
]}

Li, YM ^{[1
]}

Dai, HJ ^{[1
]}

机构：

[1] Stanford Univ, Dept Chem, Stanford, CA 94305 USA

来源：

NANO LETTERS | 2002年 / 2卷 / 04期

关键词：

D O I：

10.1021/nl015692j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The interface between biological molecules and novel nanomaterials is important to developing new types of miniature devices for biological applications. Here, the streptavidin/biotin system is used to investigate the adsorption behavior of proteins on the sides of single-walled carbon nanotubes (SWNTs). Functionalization of SWNTs by coadsorption of a surfactant and poly(ethylene glycol) is found to be effective in resisting nonspecific adsorption of streptavidin. Specific binding of streptavidin onto SWNTs is achieved by co-functionalization of nanotubes with biotin and protein-resistant polymers.

引用

页码：285 / 288

页数：4

共 20 条

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