3D-bioprinted human tissue and the path toward clinical translation

被引：44

作者：

Bliley, Jacqueline M. ^{[1
]}

Shiwarski, Daniel J. ^{[1
]}

Feinberg, Adam W. ^{[1
,2
]}

机构：

[1] Carnegie Mellon Univ, Dept Biomed Engn, Pittsburgh, PA 15213 USA

[2] Carnegie Mellon Univ, Dept Mat Sci & Engn, Pittsburgh, PA 15213 USA

来源：

SCIENCE TRANSLATIONAL MEDICINE | 2022年 / 14卷 / 666期

基金：

美国国家卫生研究院;

关键词：

3D; CONSTRUCTS; NETWORKS; PROGRESS;

D O I：

10.1126/scitranslmed.abo7047

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Three-dimensional (3D) bioprinting is a transformative technology for engineering tissues for disease modeling and drug screening and building tissues and organs for repair, regeneration, and replacement. In this Viewpoint, we discuss technological advances in 3D bioprinting, key remaining challenges, and essential milestones toward clinical translation.

引用

页数：6

共 48 条

[1] Whole-Organ Tissue Engineering: Decellularization and Recellularization of Three-Dimensional Matrix Scaffolds [J].

Badylak, Stephen F. ;

Taylor, Doris ;

Uygun, Korkut .

ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, VOL 13, 2011, 13 :27-53

[2] Navigating the Regulatory Pathways and Requirements for Tissue-Engineered Products in the Treatment of Burns in the United States [J].

Belsky, Kimberly ;

Smiell, Janice .

JOURNAL OF BURN CARE & RESEARCH, 2021, 42 (04) :774-784

[3] Writing in the granular gel medium [J].

Bhattacharjee, Tapomoy ;

Zehnder, Steven M. ;

Rowe, Kyle G. ;

Jain, Suhani ;

Nixon, Ryan M. ;

Sawyer, W. Gregory ;

Angelini, Thomas E. .

SCIENCE ADVANCES, 2015, 1 (08)

[4] Dynamic loading of human engineered heart tissue enhances contractile function and drives a desmosome-linked disease phenotype [J].

Bliley, Jacqueline M. ;

Vermeer, Mathilde C. S. C. ;

Duffy, Rebecca M. ;

Batalov, Ivan ;

Kramer, Duco ;

Tashman, Joshua W. ;

Shiwarski, Daniel J. ;

Lee, Andrew ;

Teplenin, Alexander S. ;

Volkers, Linda ;

Coffin, Brian ;

Hoes, Martijn F. ;

Kalmykov, Anna ;

Palchesko, Rachelle N. ;

Sun, Yan ;

Jongbloed, Jan D. H. ;

Bomer, Nils ;

de Boer, Rudolf A. ;

Suurmeijer, Albert J. H. ;

Pijnappels, Daniel A. ;

Bolling, Maria C. ;

van der Meer, Peter ;

Feinberg, Adam W. .

SCIENCE TRANSLATIONAL MEDICINE, 2021, 13 (603)

[5]

Clemens M., 2022, 3D NATIVES 0616

[6] Challenges in the translation and commercialization of cell therapies [J].

Dodson, Brittany P. ;

Levine, Aaron D. .

BMC BIOTECHNOLOGY, 2015, 15

[7] Dual-Stage Crosslinking of a Gel-Phase Bioink Improves Cell Viability and Homogeneity for 3D Bioprinting [J].

Dubbin, Karen ;

Hori, Yuki ;

Lewis, Kazuomori K. ;

Heilshorn, Sarah C. .

ADVANCED HEALTHCARE MATERIALS, 2016, 5 (19) :2488-2492

[8] Biomimetic design of microfluidic manifolds based on a generalised Murray's law [J].

Emerson, DR ;

Cieslicki, K ;

Gu, XJ ;

Barber, RW .

LAB ON A CHIP, 2006, 6 (03) :447-454

[9] Progress in three-dimensional bioprinting [J].

Feinberg, Adam W. ;

Miller, Jordan S. .

MRS BULLETIN, 2017, 42 (08) :557-562

[10]

Fluidform3D, 2019, PR NEWSWIRE 0801

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