Attachment and temperament profiles among the offspring of a parent with bipolar disorder

被引:25
作者
Doucette, S. [1 ]
Horrocks, J. [3 ]
Gror, P. [4 ,5 ]
Keown-Stoneman, C. [3 ]
Duffy, A. [1 ,2 ,5 ]
机构
[1] Dalhousie Univ, Dept Community Hlth & Epidemiol, Halifax, NS, Canada
[2] Univ Calgary, Dept Psychiat, Calgary, AB T2N 4Z6, Canada
[3] Univ Guelph, Dept Math & Stat, Guelph, ON N1G 2W1, Canada
[4] Univ Toronto, Dept Psychiat, Toronto, ON M5S 1A1, Canada
[5] Mood Disorders Ctr Ottawa, Ottawa, ON, Canada
基金
加拿大健康研究院;
关键词
Attachment; Bipolar disorder; High-risk studies; Temperament; Early adversity; DEPRESSION; PERSONALITY; SYMPTOMS; CHILDREN; PSYCHOPATHOLOGY; ADOLESCENCE; UNIPOLAR; LITHIUM; STRESS; TRENDS;
D O I
10.1016/j.jad.2013.01.023
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Introduction: Attachment is associated both with the risk of developing a mood disorder and temperamental profile. Relatively little is known about these associations in children of a parent with bipolar disorder (BD). The present study is a preliminary analysis of the association between attachment, temperament and psychopathology among high-risk offspring. Methods: As part of an ongoing prospective cohort study, offspring from families with one parent with BD (HR) and offspring from families with unaffected parents (C) were clinically assessed using KSADS-PL format interviews annually. Validated self-report measures of perceived attachment and temperament were completed. Results: Perceived attachment did not differentiate HR from C offspring and did not predict psychopathology or mood disorder in particular. However, high emotionality significantly predicted the risk of psychopathology in FIR offspring, where 1 standard deviation increase in emotionality significantly increased the hazard of psychopathology by a factor of 1.36 (p=0.0009) and mood disorder by a factor of 1.24 (p=0.02). Limitations: Use of retrospective measures and low sample size for some models. Conclusions: There may be no gross abnormalities in attachment among FIR compared to C offspring. It remains unclear if emotionality is a barometer of illness or a true risk factor in this population. More longitudinal research is needed to advance understanding of the influential pathways by which psychosocial risk factors impact the development of BD. This research has implications for targeted early interventions in HR youth. (C) 2013 Elsevier B.V. All rights reserved.
引用
收藏
页码:522 / 526
页数:5
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