Risk of depression and other mental health disorders in women with polycystic ovary syndrome: a longitudinal study

被引:141
|
作者
Kerchner, Angela [2 ]
Lester, Whitney [3 ]
Stuart, Scott P. [3 ]
Dokras, Anuja [1 ]
机构
[1] Univ Penn, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
[2] Univ Iowa, Roy J & Lucille A Carver Coll Med, Dept Obstet & Gynecol, Iowa City, IA USA
[3] Univ Iowa, Roy J & Lucille A Carver Coll Med, Dept Psychiat, Iowa City, IA USA
关键词
Polycystic ovary syndrome; depression; mood disorders; QUALITY-OF-LIFE; PRIME-MD; PREVALENCE; QUESTIONNAIRE; PREDICTORS; VALIDITY; UTILITY;
D O I
10.1016/j.fertnstert.2007.11.022
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To determine the conversion risk and predictors for depression in women with polycystic ovary syndrome. Design: Prospective longitudinal study. Setting: University practice. Patient(s): Subjects with polycystic ovary syndrome who had participated in a previous study. Intervention(s): None. Main Outcome Measure(s): The Primary Care Evaluation of Mental Disorders Patient Health Questionnaire was used to diagnose major depressive disorder and other depressive syndromes, anxiety syndromes, and binge eating disorder. Subjects completed a questionnaire on knowledge about polycystic ovary syndrome and treatment satisfaction. Result(s): A total of 60 of 103 subjects responded to the second survey. Mean time between the two surveys was 22 months (range 12-26 months), The overall prevalence of depression was 40% (24/60). Of these, 10 women screened positive for major depressive disorder or other depressive syndromes and 14 were receiving antidepressant medications. There were 11 new cases identified in the second survey (19% conversion). Total subjects with mood disorders in this study were 34/60 (56.6%), including 11.6% with anxiety syndromes and 23.3% with binge eating disorder. Difficulties with menstrual function, fertility, and body image (weight, hirsutism, acne) were not significantly different in women with and without depression. Conclusion(s): There is a significant risk for mood disorders (defined by the Diagnostic and Statistical Manual of Mental Disorders-IV) in women with polycystic ovary syndrome. This finding together with a high conversion risk for depression over a 1- to 2-year period underscores the importance of routine screening and aggressive treatment of mental health disorders in this population. (Fertil Steril (R) 2009;91:207-12. (c) 2009 by American Society for Reproductive Medicine.)
引用
收藏
页码:207 / 212
页数:6
相关论文
共 50 条
  • [41] Obesity and depression are risk factors for future eating disorder-related attitudes and behaviors in women with polycystic ovary syndrome
    Greenwood, Eleni A.
    Pasch, Lauri A.
    Cedars, Marcelle, I
    Huddleston, Heather G.
    FERTILITY AND STERILITY, 2020, 113 (05) : 1039 - 1049
  • [42] A comprehensive mental health care program for women with polycystic ovary syndrome: protocol for a mixed methods study
    ZareMobini, Fatemeh
    Kazemi, Ashraf
    Farajzadegan, Ziba
    REPRODUCTIVE HEALTH, 2018, 15
  • [43] Body image and mental health in women with polycystic ovary syndrome-a cross-sectional study
    Hofmann, Konstantin
    Decrinis, Claire
    Bitterlich, Norman
    Tropschuh, Katharina
    Stute, Petra
    Bachmann, Annette
    ARCHIVES OF GYNECOLOGY AND OBSTETRICS, 2025,
  • [44] Polycystic Ovary Syndrome and Depression in New Zealand Adolescents
    Milsom, Stella R.
    Nair, Sasha M.
    Ogilvie, Cara M.
    Stewart, Joanna M.
    Merry, Sally N.
    JOURNAL OF PEDIATRIC AND ADOLESCENT GYNECOLOGY, 2013, 26 (03) : 142 - 147
  • [45] Anxiety and depression in polycystic ovary syndrome: a comprehensive investigation
    Deeks, Amanda A.
    Gibson-Helm, Melanie E.
    Teede, Helena J.
    FERTILITY AND STERILITY, 2010, 93 (07) : 2421 - 2423
  • [46] Depression in polycystic ovary syndrome: Focusing on pathogenesis and treatment
    Xing, Liwei
    Xu, Jinlong
    Wei, Yuanyuan
    Chen, Yang
    Zhuang, Haina
    Tang, Wei
    Yu, Shun
    Zhang, Junbao
    Yin, Guochen
    Wang, Ruirui
    Zhao, Rong
    Qin, Dongdong
    FRONTIERS IN PSYCHIATRY, 2022, 13
  • [47] Depression, anxiety and cardiometabolic risk in polycystic ovary syndrome
    Cinar, Nese
    Kizilarslanoglu, Muhammed Cemal
    Harmanci, Ayla
    Aksoy, Duygu Yazgan
    Bozdag, Gurkan
    Demir, Basaran
    Yildiz, Bulent Okan
    HUMAN REPRODUCTION, 2011, 26 (12) : 3339 - 3345
  • [48] A prospective study of antenatal anxiety and depression in pregnant women with polycystic ovary syndrome
    Floyd, R.
    Hughes, N.
    O'Sullivan, L.
    Hevey, D.
    Murphy, N.
    Hinds, C.
    Owens, L.
    IRISH JOURNAL OF PSYCHOLOGICAL MEDICINE, 2024,
  • [49] Postnatal depression in a community-based study of women with polycystic ovary syndrome
    March, Wendy A.
    Whitrow, Melissa J.
    Davies, Michael J.
    Fernandez, Renae C.
    Moore, Vivienne M.
    ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 2018, 97 (07) : 838 - 844
  • [50] Mood disorders and quality of life in polycystic ovary syndrome
    Podfigurna-Stopa, Agnieszka
    Luisi, Stefano
    Regini, Cristina
    Katulski, Krzysztof
    Centini, Gabriele
    Meczekalski, Blazej
    Petraglia, Felice
    GYNECOLOGICAL ENDOCRINOLOGY, 2015, 31 (06) : 431 - 434