Are pharmaceutics really going supercritical?

被引：136
作者：
Pasquali, Irene [1 ]
Bettini, Ruggero [1 ]
机构：
[1] Univ Parma, Dept Pharm, I-43100 Parma, Italy
来源：
INTERNATIONAL JOURNAL OF PHARMACEUTICS | 2008年 / 364卷 / 02期
关键词：
Supercritical fluids; Micronization; Coating; Foaming; Cyclodextrin; Tissue engineering; Extrusion; Liposomes; Sterilization; Solvent removal;
D O I：
10.1016/j.ijpharm.2008.05.014
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The present work focuses on some applications of supercritical fluids in the pharmaceutical field, provides a critical review of the most recent advances and aims to give a vision on the future of this technology. In particular, processes such as particle and crystal engineering, formation of cyclodextrin complexes, coating, foaming and tissue engineering, extrusion, production of liposomes, formulation of biotechnological compounds, sterilization and solvent removal are described and discussed. (c) 2008 Elsevier B.V. All rights reserved.
引用
收藏
页码：176 / 187
页数：12
相关论文
共 116 条
[51]   Preparation of itraconazole/HP-β-CD inclusion complexes using supercritical aerosol solvent extraction system and their dissolution characteristics [J].
Lee, Sang-Yun ;
Jung, In-Il ;
Kim, Jeong-Kyu ;
Lim, Gio-Bin ;
Ryu, Jong-Hoon .
JOURNAL OF SUPERCRITICAL FLUIDS, 2008, 44 (03) :400-408
[52]   Preparation of monolithic matrices for oral drug delivery using a supercritical fluid assisted hot melt extrusion process [J].
Lyons, John G. ;
Hallinan, Mark ;
Kennedy, James E. ;
Devine, Declan M. ;
Geever, Luke M. ;
Blackie, Paul ;
Higginbotham, Clement L. .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2007, 329 (1-2) :62-71
[53]   Dense gas processing of micron-sized drug formulations incorporating hydroxypropylated and methylated beta-cyclodextrin [J].
Mammucari, R ;
Dehghani, F ;
Foster, NR .
PHARMACEUTICAL RESEARCH, 2006, 23 (02) :429-437
[54]  
METHA DB, 2001, Patent No. 6627246
[55]   Nanoparticle formation in rapid expansion of water-in-supercritical carbon dioxide microemulsion into liquid solution [J].
Meziani, MJ ;
Pathak, P ;
Beacham, F ;
Allard, LF ;
Sun, YP .
JOURNAL OF SUPERCRITICAL FLUIDS, 2005, 34 (01) :91-97
[56]   Microencapsulation of proteins by rapid expansion of supercritical solution with a nonsolvent [J].
Mishima, K ;
Matsuyama, K ;
Tanabe, D ;
Yamauchi, S ;
Young, TJ ;
Johnston, KP .
AICHE JOURNAL, 2000, 46 (04) :857-865
[57]   Characterisation of nimesulide-betacyclodextrins systems prepared by supercritical fluid impregnation [J].
Moneghini, A ;
Kikic, I ;
Perissutti, B ;
Franceschinis, E ;
Cortesi, A .
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2004, 58 (03) :637-644
[58]   Novel approach to fabricate porous sponges of poly(D,L-lactic-co-glycolic acid) without the use of organic solvents [J].
Mooney, DJ ;
Baldwin, DF ;
Suh, NP ;
Vacanti, LP ;
Langer, R .
BIOMATERIALS, 1996, 17 (14) :1417-1422
[59]   Supercritical carbon dioxide processing of active pharmaceutical ingredients for polymorphic control and for complex formation [J].
Moribe, Kunikazu ;
Tozuka, Yuichi ;
Yamamoto, Keiji .
ADVANCED DRUG DELIVERY REVIEWS, 2008, 60 (03) :328-338
[60]   Supercritical fluid processing of proteins I:: Lysozyme precipitation from organic solution [J].
Moshashaée, S ;
Bisrat, M ;
Forbes, RT ;
Nyqvist, H ;
York, P .
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2000, 11 (03) :239-245
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