Are pharmaceutics really going supercritical?

被引：136

作者：

Pasquali, Irene ^{[1
]}

Bettini, Ruggero ^{[1
]}

机构：

[1] Univ Parma, Dept Pharm, I-43100 Parma, Italy

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 2008年 / 364卷 / 02期

关键词：

Supercritical fluids; Micronization; Coating; Foaming; Cyclodextrin; Tissue engineering; Extrusion; Liposomes; Sterilization; Solvent removal;

D O I：

10.1016/j.ijpharm.2008.05.014

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The present work focuses on some applications of supercritical fluids in the pharmaceutical field, provides a critical review of the most recent advances and aims to give a vision on the future of this technology. In particular, processes such as particle and crystal engineering, formation of cyclodextrin complexes, coating, foaming and tissue engineering, extrusion, production of liposomes, formulation of biotechnological compounds, sterilization and solvent removal are described and discussed. (c) 2008 Elsevier B.V. All rights reserved.

引用

页码：176 / 187

页数：12

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