Timeliness and completeness of vaccination and risk factors for low and late vaccine uptake in young children living in rural southern Tanzania

被引:50
作者
de Waroux, Olivier Le Polain [1 ]
Schellenberg, Joanna R. Armstrong [1 ,2 ]
Manzi, Fatuma [2 ]
Mrisho, Mwifadhi [2 ]
Shirima, Kizito [2 ]
Mshinda, Hassan [2 ]
Alonso, Pedro [3 ,4 ]
Tanner, Marcel [5 ,6 ]
Schellenberg, David M. [1 ,2 ]
机构
[1] Univ London London Sch Hyg & Trop Med, Dept Infect & Trop Dis, London WC1E 7HT, England
[2] Ifakara Hlth Inst, Dar Es Salaam, Tanzania
[3] Univ Barcelona, Hosp Clin, Barcelona Ctr Int Hlth Res, E-08036 Barcelona, Spain
[4] Ctr Invest Saude Manhica, Maputo 1929, Mozambique
[5] Swiss Trop & Publ Hlth Inst, CH-4051 Basel, Switzerland
[6] Univ Basel, CH-4051 Basel, Switzerland
来源
INTERNATIONAL HEALTH | 2013年 / 5卷 / 02期
基金
比尔及梅琳达.盖茨基金会;
关键词
Vaccination; Timeliness; Coverage; Risk factors; Children; Tanzania; INFLUENZAE TYPE-B; IMMUNIZATION COVERAGE; DETERMINANTS; POPULATION; MOZAMBIQUE; COUNTRIES; BURDEN; KENYA;
D O I
10.1093/inthealth/iht006
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
We studied coverage and timeliness of vaccination and risk factors for low and delayed vaccine uptake in children aged 2 years in rural Tanzania. We used data from a cluster survey conducted in 2004, which included 1403 children. Risk factors were analysed by log-binomial regression adjusted for the clustering. The analysis was restricted to BCG, first and third dose of DiphtheriaTetanusPertussis vaccines (DTP-1 and DTP-3) and first dose of measles-containing vaccine (MCV-1). Coverage for BCG, DTP-1, DTP-3 and MCV-1 was 94, 96, 90 and 86, respectively. Delayed vaccination (1 month after the recommended age) occurred in 398/1205 (33) children for BCG, 404/1189 (34) for DTP-1, 683/990 (69) for DTP-3 and 296/643 (46) for MCV-1. Coverage was lower for all vaccines except DTP-1 in children living 5km from a healthcare facility. Delayed uptake was associated with poverty. Low and delayed MCV-1 vaccination was associated with low maternal education. Delayed BCG vaccination was associated with ethnicity and rainy season. Despite reasonably high vaccination coverage, we observed substantial vaccination delays, particularly for DTP-3 and MCV-1. We found specific factors associated with low and/or delayed vaccine uptake. These findings can help to improve strategies to reach children who remain inadequately protected.
引用
收藏
页码:139 / 147
页数:9
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