Subcutaneous phaeohyphomycosis caused by Exophiala equina, with susceptibility to eight antifungal drugs

被引：20

作者：

Najafzadeh, Mohammad Javad ^{[1
,2
]}

Suh, Moo Kyu ^{[3
]}

Lee, Myung Hoon ^{[3
]}

Ha, Gyoung Yim ^{[4
]}

Kim, Jung Ran ^{[5
]}

Kim, Tae Heung ^{[6
]}

Lee, Hyo Jin ^{[7
]}

Choi, Jong Soo ^{[7
]}

Meis, Jacques F. ^{[8
]}

De Hoog, G. Sybren ^{[9
,10
,11
]}

机构：

[1] Mashhad Univ Med Sci, Dept Parasitol & Mycol, Ghaem Hosp, Sch Med, Mashhad, Iran

[2] Mashhad Univ Med Sci, Canc Mol Pathol Res Ctr, Ghaem Hosp, Sch Med, Mashhad, Iran

[3] Dongguk Univ, Dept Dermatol, Gyeongju, South Korea

[4] Dongguk Univ, Gyeongju, South Korea

[5] Dongguk Univ, Coll Med, Gyeongju, South Korea

[6] White Skin Clin, Chang Won, South Korea

[7] Yeungnam Univ, Dept Dermatol, Coll Med, Taegu, South Korea

[8] Canisius Wilhelmina Hosp, Dept Med Microbiol & Infect Dis, Nijmegen, Netherlands

[9] CBS KNAW Fungal Biodivers Ctr, Utrecht, Netherlands

[10] Univ Amsterdam, Inst Biodivers & Ecosyst Dynam, NL-1012 WX Amsterdam, Netherlands

[11] Peking Univ, Hlth Sci Ctr, Res Ctr Med Mycol, Beijing 100871, Peoples R China

来源：

JOURNAL OF MEDICAL MICROBIOLOGY | 2013年 / 62卷

关键词：

SPINIFERA CLADE; FUNGI; DIVERSITY; FONSECAEA; SPECTRUM; DISEASE;

D O I：

10.1099/jmm.0.057406-0

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A case of subcutaneous phaeohyphomycosis caused by Exophiala equine is reported in a 75-year-old female, who showed subcutaneous abscesses on both forearms for 8 months. A lesion was initiated by inoculation with a spine from a tree. Histopathologically, suppurative granulomatous inflammation was present and short hyphal elements were observed. Upon culture greyish-black, velvety colonies of a black yeast were obtained after 3 weeks. The strain grew well at 25 degrees C, but poorly at 37 degrees C. After sequencing the internal transcribed spacer domain and the partial beta-tubulin gene, the fungus was identified as E. equine. The patient was successfully treated with fluconazole for 3 months.

引用

页码：797 / 800

页数：4

共 20 条

[1]

[Anonymous], 2008, Reference method for broth dilution antifungal susceptibility testing of yeasts

[2]

[Anonymous], 1923, ATTI DELLISTITUTO BO

[3]

Badali H, 2010, MED MYCOL, V48, P318, DOI [10.3109/13693780903148353, 10.1080/13693780903148353]

[4] Waterborne Exophiala species causing disease in cold-blooded animals [J].

de Hoog, G. S. ;

Vicente, V. A. ;

Najafzadeh, M. J. ;

Harrak, M. J. ;

Badali, H. ;

Seyedmousavi, S. .

PERSOONIA, 2011, 27 :46-72

[5]

de Hoog G.S., 2000, ATLAS CLIN FUNGI

[6] Species diversity and polymorphism in the Exophiala spinifera clade containing opportunistic black yeast-like fungi [J].

de Hoog, GS ;

Vicente, V ;

Caligiorne, RB ;

Kantarcioglu, S ;

Tintelnot, K ;

van den Ende, AHGG ;

Haase, G .

JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (10) :4767-4778

[7] Coniosporium epidermidis sp nov., a new species from human skin [J].

Li, D. M. ;

de Hoog, G. S. ;

Saunte, D. M. Lindhardt ;

Van den Ende, A. H. G. Gerrits ;

Chen, X. R. .

STUDIES IN MYCOLOGY, 2008, (61) :131-136

[8] Exophiala asiatica, a new species from a fatal case in China [J].

Li, Dong Ming ;

Li, Ruo Yu ;

De Hoog, G. S. ;

Wang, Yu Xin ;

Wang, Duan Li .

MEDICAL MYCOLOGY, 2009, 47 (01) :101-109

[9] Indoor wet cells harbour melanized agents of cutaneous infection [J].

Lian, X. ;

de Hoog, G. S. .

MEDICAL MYCOLOGY, 2010, 48 (04) :622-628

[10]

MATSUMOTO T, 1994, J MED VET MYCOL, V32, P329

← 1 2 →