Strength through Diversity

被引:182
作者
Nelson, Sacha B. [1 ,2 ]
Turrigiano, Gina G. [1 ,2 ]
机构
[1] Brandeis Univ, Dept Biol, Waltham, MA 02454 USA
[2] Brandeis Univ, Natl Ctr Behav Genom, Waltham, MA 02454 USA
关键词
D O I
10.1016/j.neuron.2008.10.020
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The remarkable versatility of the mammalian brain is made possible by a huge diversity of cellular plasticity mechanisms. These include long-term potentiation and depression at both excitatory and inhibitory synapses, as well as a variety of intrinsic and homeostatic plasticity mechanisms. A fundamental challenge for the field is to assemble our detailed knowledge of these specific mechanisms into a coherent picture of how plasticity within cortical circuits works to tune network properties.
引用
收藏
页码:477 / 482
页数:6
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