Dental stem cells for craniofacial tissue engineering

被引：24
|
作者：
Machado, Elsa [1 ]
Fernandes, Maria Helena [1 ]
Gomes, Pedro de Sousa [1 ]
机构：
[1] Univ Porto, Fac Med Dent, Lab Farmacol & Biocompatibilidade Celular, P-4200393 Oporto, Portugal
来源：
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY | 2012年 / 113卷 / 06期
关键词：
BONE-MARROW; IN-VITRO; APICAL PAPILLA; FOLLICLE CELLS; STROMAL CELLS; PULP CELLS; REGENERATION; REPAIR; DIFFERENTIATION; THERAPY;
D O I：
10.1016/j.tripleo.2011.05.039
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
This article focuses on the biological characterization and discussion of the potential application of oral-derived adult stem cells for craniofacial tissue engineering applications. The authors reviewed experimental (in vitro and in vivo) and clinical reports regarding the isolation, characterization, modulation, and translational clinical application of human precursor cell populations derived from postnatal dental tissues. Five different human dental stem/progenitor cell populations have been isolated and characterized. These postnatal populations present mesenchymal stem cell like characteristics and enjoy forceful capabilities regarding the differentiation into odontogenic/osteogenic lineages, supporting evidence-in preclinical and clinical trials-for the regeneration of oral/dental tissues. (Oral Surg Oral Med Oral Pathol Oral Radiol 2012;113:728-733)
引用
收藏
页码：728 / 733
页数：6
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