A simple and efficient one step synthesis of 1,3,4-oxadiazoles utilizing polymer-supported reagents and microwave heating

被引：89

作者：

Wang, Y ^{[1
]}

Sauer, DR ^{[1
]}

Djuric, SW ^{[1
]}

机构：

[1] Abbott Labs, High Throughput Organ Synth Grp, Med Chem Technol, Global Pharmaceut Res & Dev, Abbott Pk, IL 60064 USA

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 01期

关键词：

D O I：

10.1016/j.tetlet.2005.10.131

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,3,4-Oxadiazoles can be rapidly and efficiently synthesized from a variety of carboxylic acids and acid hydrazides in one simple step. The use of commercially available PS-PPh3 resin combined with microwave heating delivered the product 1,3,4-oxadiazoles in high yields and purities. (c) 2005 Elsevier Ltd. All rights reserved.

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页码：105 / 108

页数：4

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