Two new isopimarane diterpenoids from the endophytic fungus Xylaria sp SNB-GTC2501

被引：18

作者：

Sorres, Jonathan ^{[1
]}

Nirma, Charlotte ^{[1
]}

Toure, Seinde ^{[1
]}

Eparvier, Veronique ^{[1
]}

Stien, Didier ^{[1
,2
]}

机构：

[1] Univ Paris 11, CNRS, Inst Chim Subst Nat, F-91198 Gif Sur Yvette, France

[2] Univ Paris 04, CNRS, LBBM, Observ Oceanol, F-66650 Banyuls Sur Mer, France

来源：

TETRAHEDRON LETTERS | 2015年 / 56卷 / 31期

关键词：

Xylaria sp; Endophytic fungus; Isopimarane; SECONDARY METABOLITES; DIVERSITY;

D O I：

10.1016/j.tetlet.2015.06.022

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two new isopimarane diterpenoids, xylabisboein A (1) and B (2), as well as three known secondary metabolites (i.e., (-)-5-methylmellein (3), mellein-5-carboxylic acid (4) and ergosterol peroxide (5)), were isolated from a solid culture of the endophytic fungus Xylaria sp. SNB-GTC2501. The structures were elucidated by spectroscopic analysis and the absolute configuration of xylabisboein A (1) was determined by X-ray crystallographic analysis. All of the compounds were tested for their antimicrobial and cytotoxic activities. (C) 2015 Published by Elsevier Ltd.

引用

页码：4596 / 4598

页数：3

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