The colors of adipose tissue

被引:62
作者
Frigolet, Maria E. [1 ]
Gutierrez-Aguilar, Ruth [1 ]
机构
[1] Hosp Infantil Mexico Dr Federico Gomez, Lab Metab Dis Obes & Diabet, Mexico City, DF, Mexico
来源
GACETA MEDICA DE MEXICO | 2020年 / 156卷 / 02期
关键词
Adipose tissue; Adipocyte; Metabolism; DIET-INDUCED OBESITY; DE-NOVO LIPOGENESIS; BROWN ADIPOCYTES; INSULIN-RESISTANCE; FAT; BEIGE; THERMOGENESIS; PROTEIN; HOMEOSTASIS; REVERSAL;
D O I
10.24875/GMM.M20000356
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Adipose tissue is an endocrine organ with high metabolic activity. Countless adipose tissue-secreted adipokines and lipokines, as well as peptides and lipids with biological activity have thus far been discovered. Both white and brown and beige adipose tissue are known to contribute to energy homeostasis and metabolic regulation. The purpose of this review is to report on the most recent findings related to adipose tissue according to its color and its relationship with metabolic alterations associated with obesity. After a review of the specialized literature, white, brown and beige adipocyte populations were identified to be able to coexist within the same structure, and to modify global metabolic state in physiological or pathological situations.
引用
收藏
页码:142 / 149
页数:8
相关论文
共 62 条
[1]   Mechanisms of Impaired Brown Adipose Tissue Recruitment in Obesity [J].
Alcala, Martin ;
Calderon-Dominguez, Maria ;
Serra, Dolors ;
Herrero, Laura ;
Viana, Marta .
FRONTIERS IN PHYSIOLOGY, 2019, 10
[2]  
[Anonymous], 1983, HISTOLOGY CELL TISSU
[3]  
Bays Harold E, 2008, Expert Rev Cardiovasc Ther, V6, P343, DOI 10.1586/14779072.6.3.343
[4]   A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis [J].
Bostroem, Pontus ;
Wu, Jun ;
Jedrychowski, Mark P. ;
Korde, Anisha ;
Ye, Li ;
Lo, James C. ;
Rasbach, Kyle A. ;
Bostroem, Elisabeth Almer ;
Choi, Jang Hyun ;
Long, Jonathan Z. ;
Kajimura, Shingo ;
Zingaretti, Maria Cristina ;
Vind, Birgitte F. ;
Tu, Hua ;
Cinti, Saverio ;
Hojlund, Kurt ;
Gygi, Steven P. ;
Spiegelman, Bruce M. .
NATURE, 2012, 481 (7382) :463-U72
[5]   RECOMBINANT MOUSE OB PROTEIN - EVIDENCE FOR A PERIPHERAL SIGNAL LINKING ADIPOSITY AND CENTRAL NEURAL NETWORKS [J].
CAMPFIELD, LA ;
SMITH, FJ ;
GUISEZ, Y ;
DEVOS, R ;
BURN, P .
SCIENCE, 1995, 269 (5223) :546-549
[6]   Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism [J].
Cao, Haiming ;
Gerhold, Kristin ;
Mayers, Jared R. ;
Wiest, Michelle M. ;
Watkins, Steven M. ;
Hotamisligil, Goekhan S. .
CELL, 2008, 134 (06) :933-944
[7]  
Celi FS, 2017, RES PERSPECTIVES END
[8]   Palmitoleate Reverses High Fat-induced Proinflammatory Macrophage Polarization via AMP-activated Protein Kinase (AMPK) [J].
Chan, Kenny L. ;
Pillon, Nicolas J. ;
Sivaloganathan, Darshan M. ;
Costford, Sheila R. ;
Liu, Zhi ;
Theret, Marine ;
Chazaud, Benedicte ;
Klip, Amira .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2015, 290 (27) :16979-16988
[9]   Transdifferentiation properties of adipocytes in the adipose organ [J].
Cinti, Saverio .
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2009, 297 (05) :E977-E986
[10]   EFFECTS OF PARABIOSIS OF OBESE WITH DIABETES AND NORMAL MICE [J].
COLEMAN, DL .
DIABETOLOGIA, 1973, 9 (04) :294-298