Aging and innate immunity

被引：222
作者：
Solana, Rafael [1 ]
Pawelec, Graham
Tarazona, Raquel
机构：
[1] Univ Cordoba, Dept Cellular Biol Physiol & Immunol, E-14004 Cordoba, Spain
[2] Univ Tubingen, Med Res Ctr, D-72076 Tubingen, Germany
[3] Univ Extremadura, Dept Physiol, Immunol Unit, E-10071 Caceres, Spain
来源：
IMMUNITY | 2006年 / 24卷 / 05期
关键词：
D O I：
10.1016/j.immuni.2006.05.003
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Adaptive immunity undergoes severe deterioration with age and represents the main problem in the elderly. However, evidence accumulated over the last decade supports the hypothesis that aging also has a profound impact on innate immunity, which in turn markedly impacts the health and longevity of older people.
引用
收藏
页码：491 / 494
页数：4
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