Two new compounds from the fungus Penicillium crustosum YN-HT-15

被引:3
作者
Liu, Yan-Ping [1 ,2 ]
Chen, Gang [1 ,2 ]
Wang, Hai-Feng [1 ,2 ]
Zhang, Xiao-Li [1 ,2 ]
Pei, Yue-Hu [1 ,2 ]
机构
[1] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Shenyang 110016, Peoples R China
[2] Shenyang Pharmaceut Univ, Key Lab Struct Based Drug Design & Discovery, Minist Educ, Shenyang 110016, Peoples R China
关键词
fungus; Penicillium crustosum; second metabolites; 1-(2; 4-dihydroxy-5-methyl-3-methylsulfanylmethylphenyl)-ethanone; R-3-(3-acetyl-2; 6-dihydroxy-5-methylphenyl)-2-methyl-propionic acid methyl ester;
D O I
10.1080/10286020.2013.867851
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Our current natural product program researches the second metabolites of a fungus Penicilliumcrustosum YN-HT-15 isolated from the red soil (Yunnan Province, China), to discover potential antitumor chemical entities. Two new compounds were isolated from the ethyl acetate extract of the fermentation broth of the fungus, and their structures were characterized as 1-(2,4-dihydroxy-5-methyl-3-methylsulfanylmethyl-phenyl)-ethanone (1) and R-3-(3-acetyl-2,6-dihydroxy-5-methylphenyl)-2-methyl-propionic acid methyl ester (2) on the basis of spectroscopic data.
引用
收藏
页码:281 / 284
页数:4
相关论文
共 4 条
[1]   Marine natural products [J].
Blunt, John W. ;
Copp, Brent R. ;
Keyzers, Robert A. ;
Munro, Murray H. G. ;
Prinsep, Michele R. .
NATURAL PRODUCT REPORTS, 2012, 29 (02) :144-222
[2]   Asymmetric Synthesis of α-Alkylated N-Sulfinyl Imidates as New Chiral Building Blocks [J].
Colpaert, Filip ;
Mangelinckx, Sven ;
Verniest, Guido ;
De Kimpe, Norbert .
JOURNAL OF ORGANIC CHEMISTRY, 2009, 74 (10) :3792-3797
[3]   Myceligenerans xiligouense gen. nov., sp nov., a novel hyphae-forming member of the family Promicromonosporaceae [J].
Cui, XL ;
Schumann, P ;
Stackebrandt, E ;
Kroppenstedt, RM ;
Pukall, R ;
Xu, LH ;
Rohde, M ;
Jiang, CL .
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, 2004, 54 :1287-1293
[4]   Two new compounds from marine Streptomyces sp FX-58 [J].
Huang, Y. -F. ;
Tian, L. ;
Sun, Y. ;
Pei, Y. -H. .
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2006, 8 (06) :495-498