Cerebellar medulloblastoma in the elderly

被引:12
作者
Huppmann, Alison R. [1 ]
Orenstein, Jan M. [1 ]
Jones, Robert V. [1 ]
机构
[1] George Washington Univ, Med Ctr, Dept Pathol, Washington, DC 20037 USA
关键词
Medulloblastoma; Elderly; Cerebellum; Brain neoplasms; INTRAOPERATIVE DIAGNOSIS; STRATIFICATION; PROGNOSIS; SYSTEM; ADULTS;
D O I
10.1016/j.anndiagpath.2007.06.002
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Although medulloblastoma is the most common central nervous system malignancy in children, cases are much less common in adults. Moreover, this tumor is exceedingly rare in patients older than 65 years. Analysis of previous case reports reveals that medulloblastoma in the elderly is more commonly seen in males in a lateral location; histologically, medulloblastomas in aged individuals usually belong to the classic subtype. During intraoperative consultation, the pathologist should consider medulloblastoma in the differential diagnosis of a cerebellar mass in the elderly because cytologic features may overlap with metastatic small cell carcinoma or lymphoma. We present a case of medulloblastoma in a 66-year-old man and review the literature oil the subject. (c) 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码:55 / 59
页数:5
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