Biological and related applications of pillar[n]arenes

被引：154

作者：

Sathiyajith, CuhaWijay ^{[1
]}

Shaikh, Rafik Rajjak ^{[1
]}

Han, Qian ^{[1
]}

Zhang, Yue ^{[2
]}

Meguellati, Kamel ^{[1
]}

Yang, Ying-Wei ^{[1
]}

机构：

[1] Jilin Univ, Coll Chem, Int Joint Res Lab Nanomicro Architecture Chem NMA, 2699 Qianjin St, Changchun 130012, Peoples R China

[2] Harbin Med Univ, Clin Coll 1, 23 Youzheng St, Harbin 150001, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 04期

基金：

中国国家自然科学基金;

关键词：

HOST-GUEST COMPLEXATION; CONTROLLED DRUG-RELEASE; RESPONSIVE SUPRAMOLECULAR VESICLES; PATHOGENIC BACTERIAL LECTINS; AGGREGATION-INDUCED-EMISSION; METAL-ORGANIC FRAMEWORKS; SOLID-PHASE EXTRACTION; MOLECULAR RECOGNITION; MULTIDRUG-RESISTANCE; GOLD NANOPARTICLES;

D O I：

10.1039/c6cc08967d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Pillar[n] arenes are a new class of synthetic supramolecular macrocycles streamlined by their particular pillarshaped architecture which consists of an electron-rich cavity and two fine-tuneable rims. The ease and diversity of the functionalization of the two rims open possibilities for the design of new architectures, topological isomers, and scaffolds. Significantly, this emerging class of macrocyclic receptors offers a unique platform for biological purposes. This review article covers the most recent contributions from the pillar[n] arene field in terms of artificial membrane transport systems, controlled drug delivery systems, biomedical imaging, biosensors, cell adhesion, fluorescent sensing, and pesticide detection based on hostguest interactions. The review also uniquely describes the properties of sub-units that make pillar[n] arenes suitable for biological applications and it provides a detailed outline for the design of new innovative pillar-like structures with specific properties to open up a new avenue for pillar[n] arene chemistry.

引用

页码：677 / 696

页数：20

共 202 条

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