Synthesis of 5-arylidene-2-aryl-3-(benzotriazoloacetamidyl)-1,3-thiazolidin-4-ones as analegesic and antimicrobial agents

被引：0

作者：

Asati, KC ^{[1
]}

Srivastava, SK ^{[1
]}

Srivastava, SD ^{[1
]}

机构：

[1] Dr Hari Singh Gour Univ, Dept Chem, Synthet Organ Chem Lab, Sagar 470003, MP, India

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2006年 / 45卷 / 02期

关键词：

thiazolidinon-arylidenes; analgesic agents; anti-minicrobial agents; benzotriazole; ethyl chloroacetate;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Benzotriazole on reaction with ethyl chloroacetate affords 1, which on treatment with hydrazine hydrate yields 2. Condensation of N-1(acetohydrazido)benzotriazole 2 with various carbonyls gives arylidene acetohydrazido benzotriazoles 3 which on cycloaddition with mercaptoacetic acid yields the corresponding 4-thiazolidinoncs 4. which on reaction with various carbonyl compounds afford 5-arylidene-2-aryl-benzotriazoloacetamidyl-1,3-thiazolidin-4-ones 5.

引用

页码：526 / 531

页数：6