Randomised controlled trial evaluating the efficacy of wrap therapy for wound healing acceleration in patients with NPUAP stage II and III pressure ulcer

被引:15
作者
Bito, Seiji [1 ]
Mizuhara, Akihiro [2 ]
Oonishi, Sandai
Takeuchi, Kensuke [2 ]
Suzuki, Masatsune [3 ]
Akiyama, Kazuhiro [4 ]
Kobayashi, Kazuyo [5 ]
Matsunaga, Kayoko [6 ]
机构
[1] Natl Hosp Org, Tokyo Med Ctr, Div Clin Epidemiol, Tokyo, Japan
[2] Sanwa Med Corp, Higashi Washinomiya Hosp, Saitama, Japan
[3] Tsukuba Med Ctr Hosp, Dept Gen Internal Med, Tsukuba, Ibaraki, Japan
[4] Tokatsu Clin Hosp, Matsudo, Chiba, Japan
[5] Wakaba Ostomy Ctr, Tokyo, Japan
[6] Fujita Hlth Univ, Sch Med, Dept Dermatol, Toyoake, Aichi 47011, Japan
来源
BMJ OPEN | 2012年 / 2卷 / 01期
关键词
D O I
10.1136/bmjopen-2011-000371
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives: To evaluate if 'wrap therapy' using food wraps, which is widely used in Japanese clinical sites, is not inferior when compared to guideline adhesion treatments. Design: Multicentre, prospective, randomised, open, blinded endpoint clinical trial. Setting: 15 hospitals in Japan. Patients: 66 older patients with new National Pressure Ulcer Advisory Panel stage II or III pressure ulcers. Interventions: Of these 66 patients, 31 were divided into the conventional treatment guidelines group and 35 into the wrap therapy group. Main outcome measures: The primary end point was the period until the pressure ulcers were cured. The secondary end point was a comparison of the speed of change in the Pressure Ulcer Scale for Healing score. Results: 64 of the 66 patients were analysed. The estimated mean period until healing was 57.5 days (95% CI 45.2 to 69.8) in the control group as opposed to 59.8 days (95% CI 49.7 to 69.9) in the wrap therapy group. By the extent of pressure ulcer infiltration, the mean period until healing was 16.0 days (95% CI 8.1 to 23.9) in the control group as opposed to 18.8 days (95% CI 10.3 to 27.2) in the wrap therapy group with National Pressure Ulcer Advisory Panel stage II ulcers, and 71.8 days (95% CI 61.4 to 82.3) as opposed to 63.2 days (95% CI 53.0 to 73.4), respectively, with stage III ulcers. There is no statistical significance in difference in Pressure Ulcer Scale for Healing scores. Conclusions: It might be possible to consider wrap therapy as an alternative choice in primary care settings as a simple and inexpensive dressing care. Clinical Trial registration: UMIN Clinical Trials Registry UMIN000002658. Summary protocol is available on https://upload.umin.ac.jp/cgi-bin/ctr/ctr.cgi?function=brows&action=brows&type=detail&recptno=R000003235&admin=0&language=J
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页数:8
相关论文
共 30 条
[1]   Decubitus direct current treatment (DDCT) of pressure ulcers: Results of a randomized double-blinded placebo controlled study [J].
Adunsky, A ;
Ohry, A .
ARCHIVES OF GERONTOLOGY AND GERIATRICS, 2005, 41 (03) :261-269
[2]  
Agency for Health Care Policy and Research, 1994, PRES ULC TREATM CLIN, V15, P1
[3]  
[Anonymous], OSTOMY WOUND MANAGE
[4]  
[Anonymous], 2002, JPN J PU
[5]   Wrap for leg ulcers [J].
Bailey, KA .
AMERICAN JOURNAL OF NURSING, 1996, 96 (06) :17-17
[6]   Sequential treatment with calcium alginate dressings and hydrocolloid dressings accelerates pressure ulcer healing in older subjects: A multicenter randomized trial of sequential versus nonsequential treatment with hydrocolloid dressings alone [J].
Belmin, J ;
Meaume, S ;
Rabus, MT ;
Bohbot, S .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2002, 50 (02) :269-274
[7]  
Bishop S M, 2003, J Wound Care, V12, P125
[8]   Protocol for the successful treatment of pressure ulcers [J].
Brem, H ;
Lyder, C .
AMERICAN JOURNAL OF SURGERY, 2004, 188 (1A) :9S-17S
[9]  
Cullum N, 2001, Health Technol Assess, V5, P1
[10]   Healing pressure ulcers with collagen or hydrocolloid: A randomized, controlled trial [J].
Graumlich, JF ;
Blough, LS ;
McLaughlin, RG ;
Milbrandt, JC ;
Calderon, CL ;
Agha, SA ;
Scheibel, LW .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2003, 51 (02) :147-154