Histologic and clinical significance of atypical glandular cells on pap smears

被引:19
作者
Daniel, A
Barreth, D
Schepansky, A
Johnson, G
Capstick, V
Faught, W
机构
[1] Univ Alberta, Royal Alexandra Hosp, Dept Obstet & Gynecol, Edmonton, AB T5H 3V9, Canada
[2] Dynacare Kasper Med Labs, Edmonton, AB, Canada
关键词
atypical glandular cells; dysplasia; cancer;
D O I
10.1016/j.ijgo.2005.08.009
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To determine the association between atypical glandular cells (AGC) on Pap smear and clinically significant histology, in a large health region. Methods: A cytologic database of over one million Pap smears was reviewed for a result of AGUS/AGC. Cytologic and histologic follow up was obtained to establish the presence of significant histology. Results: 456 patients available for follow up had AGUS/AGC cytology results (0.043% of all Pap smear. results). 197(45.2%) patients had a clinically significant diagnosis including 40 with adenocarcinoma in situ (AIS) of the cervix and 48 with endometrial cancer. Conclusion: AGC on a Pap smear is frequently associated with a clinically significant diagnosis. (c) 2005 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:238 / 242
页数:5
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