Biologically active triterpene saponins from callus tissue of Polygala amarella

被引：18
作者：
Desbène, S
Hanquet, B
Shoyama, Y
Wagner, H
Lacaille-Dubois, MA
机构：
[1] Univ Bourgogne, Fac Pharm, Lab Pharmacognosie, F-21033 Dijon, France
[2] Univ Bourgogne, Lab Synthese & Electrosysthese, CNRS, UMR 5632, F-21004 Dijon, France
[3] Kyushu Univ, Fac Pharmaceut Sci, Dept Pharmacognosy, Fukuoka, Japan
[4] Univ Munich, Inst Pharmazeut Biol, D-80333 Munich, Germany
来源：
JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 06期
关键词：
D O I：
10.1021/np980577i
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
A new bioactive saponin (1), together with a known saponin (polygalasaponin XXVIII) has been isolated from the callus tissue culture of Polygala amarella. Based on spectroscopic data, especially direct and long-range heteronuclear 2D NMR analysis and on chemical transformations, the structure of 1 was elucidated as 3-O-beta-D-glucopyranosyl presenegenin-28-O-beta-D-galactopyranosyl-(1 --> 3)-beta-D-xylopyranosyl-(1 --> 4)-alpha-L-rhamnopyranosyl-(1 --> 2)-[beta-D-glucopyranosyl-(1 --> 3)]-beta-D-fucopyranoside. Both saponins showed significant immunological properties based on the enhancement of granulocyte phagocytosis in vitro.
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收藏
页码：923 / 926
页数：4
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