STR primer concordance study

被引：68

作者：

Budowle, B

Masibay, A

Anderson, SJ

Barna, C

Biega, L

Brenneke, S

Brown, BL

Cramer, J

DeGroot, GA

Douglas, D

Duceman, B

Eastman, A

Giles, R

Hamill, J

Haase, DJ

Janssen, DW

Kupferschmid, TD

Lawton, T

Lemire, C

Llewellyn, B

Moretti, T

Neves, J

Palaski, C

Schueler, S

Sgueglia, J

Sprecher, C

Tomsey, C

Yet, D

机构：

[1] FBI, Lab Div, Washington, DC 20535 USA

[2] FBI, FSRU, Quantico, VA 22135 USA

[3] GeneScreen, Dallas, TX 75207 USA

[4] Illinois State Police Res & Dev Lab, Springfield, IL 62702 USA

[5] Kansas Bur Invest, Topeka Headquarters Lab, Topeka, KS 66612 USA

[6] Maine State Police Crime Lab, Augusta, ME 04333 USA

[7] Massachusetts State Police Crime Lab, Sudbury, MA 01776 USA

[8] Michigan State Police, Forens Lab E Lansing, E Lansing, MI 48823 USA

[9] Missouri Highway Patrol, Forens Lab, Jefferson City, MO 65101 USA

[10] New York State Police Crime Lab, Albany, NY 12226 USA

[11] Penn State Police DNA Lab, Greensburg, PA 15601 USA

[12] Promega Corp, Madison, WI 53711 USA

[13] S Dakota Forens Lab, Pierre, SD 57501 USA

[14] Wisconsin State Lab Milwaukee, Milwaukee, WI 53204 USA

来源：

FORENSIC SCIENCE INTERNATIONAL | 2001年 / 124卷 / 01期

关键词：

AmpFISTR (R) Profiler Plus (TM) kit; AmpFISTR (R) COfiler (TM) kit; PowerPlex (R) 16 kit; PowerPlex (R) 2.1 kit; CODIS; concordance; primers; STR; stochastic effects; allele dropout; penta D; penta E; Hardy-Weinberg expectations;

D O I：

10.1016/S0379-0738(01)00563-1

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

Over 1500 population database samples comprising African Americans, Caucasians, Hispanics, Native Americans, Chamorros and Filipinos were typed using the PowerPlex(R) 16 and the Profiler Plus(TM)/COfiler(TM) kits. Except for the D8S1179 locus in Chamorros and Filipinos from Guam, there were eight examples in which a typing difference due to allele dropout was observed. At the D8S1179 locus in the population samples from Guam, there were 13 examples of allele dropout TM observed when using the Profiler Plus kit. The data support that the primers used in the PowerPlex(R) 16, Profiler Plus, and COfiler(TM) kits are reliable for typing reference samples that are for use in CODIS. In addition, allele frequency databases have been established for the STR loci Penta D and Penta E. Both loci are highly polymorphic. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：47 / 54

页数：8

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