Development of gold nanorod-based localized surface plasmon resonance optical fiber biosensor

被引:0
|
作者
Cao, Jie [1 ]
Sun, Tong [1 ]
Grattan, Kenneth T. V. [1 ]
机构
[1] City Univ London, Sch Engn & Math Sci, London EC1V 0HB, England
来源
22ND INTERNATIONAL CONFERENCE ON OPTICAL FIBER SENSORS, PTS 1-3 | 2012年 / 8421卷
关键词
localized surface plasmon resonance; gold nanorods; optical fiber sensor; biosensor;
D O I
10.1117/12.975160
中图分类号
TP7 [遥感技术];
学科分类号
081102 ; 0816 ; 081602 ; 083002 ; 1404 ;
摘要
A localized surface plasmon resonance (LSPR) based optical fiber biosensor using gold nanorods has been developed. The LSPR optical fiber sensor was fabricated by immobilizing gold nanorods at the distal end of a multimode fiber. The surface of gold nanorods was further functionalized with human IgG to create a biosensor to detect anti-human IgG. The peak shift of the longitudinal plasmon wavelength of gold nanorod was monitored as a function of the refractive index change. The results show that refractive index sensitivity of this sensor is 506 nm/RIU, and the limit of detection for antihuman IgG is 3 nM.
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页数:4
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