A case of invasive pulmonary mucormycosis resulting from short courses of corticosteroids in a well-controlled diabetic patient

被引:58
作者
Hoang, Kathy [1 ]
Abdo, Tony [2 ]
Reinersman, J. Matthew [3 ]
Lu, Rufei [4 ]
Higuita, Nelson Ivan Agudelo [1 ]
机构
[1] Univ Oklahoma, Hlth Sci Ctr, Sect Infect Dis, Dept Internal Med, 800 Stanton L Young Blvd, Oklahoma City, OK 73104 USA
[2] Univ Oklahoma, Hlth Sci Ctr, Dept Internal Med, Sect Pulm Crit Care & Sleep Med, 800 Stanton L Young Blvd, Oklahoma City, OK 73104 USA
[3] Univ Oklahoma, Hlth Sci Ctr, Dept Surg, Div Cardiac Thorac & Vasc Surg, 800 Stanton L,Young Blvd, Oklahoma City, OK 73104 USA
[4] Univ Oklahoma, Dept Pathol & Med, Hlth Sci Ctr, 940 Stanton L Young Blvd, Oklahoma City, OK 73104 USA
关键词
Mucormycosis; Pulmonary mucormycosis; Steroid-induced hyperglycemia; Corticosteroid; Isavuconazole; INFECTION; RISK;
D O I
10.1016/j.mmcr.2020.05.008
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
A patient with well-controlled type 2 diabetes mellitus developed a severe pulmonary infection secondary to Rhizopus spp. after receiving short courses of corticosteroids for a respiratory tract infection. He recovered after an aggressive surgical intervention and treatment with isavuconazole. Patients on chronic corticosteroid therapy have a higher risk for pulmonary mucormycosis, but there are much fewer reports of mucormycosis occurring in patients after only short courses of steroid therapy.
引用
收藏
页码:22 / 24
页数:3
相关论文
共 20 条
[1]   Invasive fungal infections associated with prior respiratory viral infections in immunocompromised hosts [J].
Ajmal, Saira ;
Mahmood, Maryam ;
Abu Saleh, Omar ;
Larson, Jenifer ;
Sohail, M. Rizwan .
INFECTION, 2018, 46 (04) :555-558
[2]  
[Anonymous], 2019, J FUNGI, DOI DOI 10.3390/JOF5010026
[3]  
[Anonymous], 2014, RESP CARE, DOI DOI 10.4187/RESPCARE.03174
[4]  
[Anonymous], 2018, ANTIMICROB AGENTS CH
[5]  
[Anonymous], 2019, MICROORGANISMS, DOI DOI 10.3390/MICROORGANISMS7110531
[6]  
de Mol P, 2009, NETH J MED, V67, P25
[7]   Characteristics of pulmonary mucormycosis and predictive risk factors for the outcome [J].
Feng, Jun ;
Sun, Xuefeng .
INFECTION, 2018, 46 (04) :503-512
[8]  
Ferguson AD, 2007, J AM OSTEOPATH ASSOC, V107, P491
[9]   CotH3 mediates fungal invasion of host cells during mucormycosis [J].
Gebremariam, Teclegiorgis ;
Liu, Mingfu ;
Luo, Guanpingsheng ;
Bruno, Vincent ;
Phan, Quynh T. ;
Waring, Alan J. ;
Edwards, John E., Jr. ;
Filler, Scott G. ;
Yeaman, Michael R. ;
Ibrahim, Ashraf S. .
JOURNAL OF CLINICAL INVESTIGATION, 2014, 124 (01) :237-250
[10]   Pathogenesis of Mucormycosis [J].
Ibrahim, Ashraf S. ;
Spellberg, Brad ;
Walsh, Thomas J. ;
Kontoyiannis, Dimitrios P. .
CLINICAL INFECTIOUS DISEASES, 2012, 54 :S16-S22