Contraception for Men: A Breakthrough New Approach

被引：9
作者：
Bremner, William J. [1 ]
机构：
[1] Univ Washington, Dept Med, Seattle, WA 98195 USA
来源：
CELL | 2012年 / 150卷 / 04期
关键词：
1ST BROMODOMAIN; SPERMATOGENESIS; INHIBITION; BRDT;
D O I：
10.1016/j.cell.2012.07.027
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
There has not been a new reversible contraceptive for men since the development of the condom, centuries ago. Matzuk et al. describe a new molecular approach using administration of a small molecule to directly and reversibly inhibit spermatogenesis in mice by blocking the function of a testicular bromodomain without apparent adverse effect on the organism or offspring.
引用
收藏
页码：667 / 668
页数：2
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