We take the orbital design and control strategy of Chang'e-3 soft-landing as the research object in this paper. First we should establish the three-dimension dynamical model of uniform sphere and the dynamical model of soft-landing under the selenocentric inertial system, then we adopt a new optimization algorithm, namely Ant Colony Algorithm, ACA, to study the lunar soft-landing trajectory optimization problem, and calculate the Chang'e-3 landing orbit. Finally, we use Hohmann transfer to figure out the total time of six stages first, and we use the MATLAB software simulation and calculate the Moon landing site step by step. Then we use the Excel software to fit the 6 stages so as to calculate the corresponding time of the 6 stages respectively. Based on the detailed analysis of Chang'e-3 landing orbit, we adopt covariance analysis to analyze the orbital error caused by the error source of the orbital initial error. We make the complexity of the solving process which is difficult to achieve be reduced, and we evaluate and promote the model, namely, sensitivity analysis, to make it be able to be better used in the actual production and life.