Biomaterial mimicking indole-3-acetic acid based gold nanocomposite hydrogels

In this study, the gold nanoparticles loaded indole-3-acetic acid (IAA) based nanocomposite hydrogels have been prepared using ethylene glycol (EG) and citric acid (CA) by condensation polymerization without crosslinking agent. Two different concentrations of nanocomposite hydrogels have prepared and named as ICE-Au-1 and ICE-Au-2. Moreover, the resulting nanocomposite hydrogels were confirmed by FT-IR, UV and SEM analysis. The TEM and EDX system were used to found the shape and composition of gold nanoparticles in prepared nanocomposite hydrogels. The variation of swelling have noticed in acidic pH than the alkaline medium due to binding of gold nanoparticles. The results of biological properties such as antimicrobial, antioxidant and biocompatible studies were also critically discussed. Thus, the aim of this work was to study various composition of gold nanocomposite hydrogels and its relation with stoichiometric concentration of monomers to evaluate good biomedical material in mere future. [GRAPHICS] .