Application of modified antisense oligonucleotides and siRNAs as antiviral drugs

被引:14
|
作者
Wagner, Anke [1 ]
Bock, Claus-Thomas [2 ]
Fechner, Henry [3 ]
Kurreck, Jens [3 ]
机构
[1] Berlin Univ Technol, BioNukleo, Dept Bioproc Engn, Berlin, Germany
[2] Robert Koch Inst, Dept Infect Dis, Berlin, Germany
[3] Berlin Univ Technol, Inst Biotechnol, Dept Appl Biochem, Berlin, Germany
关键词
antisense oligonucleotide; antiviral therapy; delivery system; modified nucleotides; post-transcriptional gene silencing; siRNAs; EBOLA-VIRUS; RNA INTERFERENCE; DISCOVERY; INFECTION; PRIMATES;
D O I
10.4155/fmc.15.114
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
引用
收藏
页码:1637 / 1642
页数:6
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