Diagnosis and Staging of Medication-Related Osteonecrosis of the Jaw

被引：52
作者：
Ruggiero, Salvatore L. [1 ,2 ]
机构：
[1] SUNY Stony Brook, Sch Dent Med, Dept Oral & Maxillofacial Surg, Stony Brook, NY 11794 USA
[2] Hofstra North Shore LIJ Sch Med, Div Oral & Maxillofacial Surg, New York, NY 11040 USA
来源：
ORAL AND MAXILLOFACIAL SURGERY CLINICS OF NORTH AMERICA | 2015年 / 27卷 / 04期
关键词：
Osteonecrosis; Medication-related osteonecrosis of the jaw; Jaw necrosis; Antiresorptive therapy; Antiangiogenic therapy; BISPHOSPHONATE-RELATED OSTEONECROSIS; SURGEONS POSITION PAPER; RISK-FACTORS; AMERICAN ASSOCIATION; CANCER-PATIENTS; BREAST-CANCER; PREVENTION; THERAPY; DENOSUMAB; SECONDARY;
D O I：
10.1016/j.coms.2015.06.008
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
The relationship between osteonecrosis of the jaw and bisphosphonate therapy was initially established more than 10 years ago. Since that time, our understanding of this disease process has evolved as the direct result of clinical, basic science, and animal research initiatives. Medication-related osteonecrosis of the jaw (MRONJ) is a well-known entity now known to be associated with various antiresorptive therapies and recently with antiangiogenic medications. This article reviews the recently modified diagnostic criteria for MRONJ with a focus on the clinical, histopathologic, and imaging characteristics of this disease process.
引用
收藏
页码：479 / +
页数：10
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