Evaluation of water uptake and mechanical properties of biomedical polymers

被引：0
作者：
Vidovic, Elvira [1 ]
Klee, Doris [2 ]
Hoecker, Hartwig [3 ]
机构：
[1] Univ Zagreb, Fac Chem Engn & Technol, Zagreb 10000, Croatia
[2] Rhein Westfal TH Aachen, D-52062 Aachen, Germany
[3] Rhein Westfal TH Aachen, Dept Text & Macromol Chem, D-52056 Aachen, Germany
来源：
JOURNAL OF APPLIED POLYMER SCIENCE | 2013年 / 130卷 / 05期
关键词：
biomaterials; mechanical properties; swelling; INDUCED PHASE-SEPARATION; IN-VITRO DEGRADATION; HYDROLYTIC DEGRADATION; ACID COMPOSITES; SCAFFOLDS; BONE; POLY(LACTIDE-CO-GLYCOLIDE); CARBONATE; FIXATION; HYDROGEL;
D O I：
10.1002/app.39624
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Poly(vinyl alcohol) grafted with poly(d,l-lactide) or poly(d,l-lactide-co-glycolide) oligomers, were synthesized in our laboratory and investigated with respect to their potential for tissue engineering applications. In order to understand their structure-properties relationships the effect of length and composition as well as number of polyester grafts on PVA backbone chain on water uptake capability and hydrophilicity/hydrophobicity balance and on mechanical properties of hydrogels was evaluated. The E moduli of hydrogels display values between 0.01 and 100 MPa. The results indicate the route for the development of polymers with a very broad range of properties similar to those of natural cartilage tissue. (c) 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 130: 3682-3688, 2013
引用
收藏
页码：3682 / 3688
页数：7
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