Fabrication of PLGA Based Tissue Engineering Scaffolds via Photocuring and Salt Leaching Techniques

被引：14
作者：
Cicek, Cigdem [1 ]
Cakmakci, Emrah [1 ]
Kayaman-Apohan, Nilhan [1 ]
Arslan, Mehmet [2 ]
Kuruca, Serap Erdem [2 ]
机构：
[1] Marmara Univ, Dept Chem, Istanbul, Turkey
[2] Istanbul Univ, Istanbul Fac Med, Dept Physiol, Istanbul, Turkey
来源：
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS | 2013年 / 62卷 / 14期
关键词：
Photocuring; PLGA; salt leaching; tissue engineering; POROGEN; BONE;
D O I：
10.1080/00914037.2013.769232
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
The authors aimed to prepare UV curable porous scaffolds via photo curing and salt leaching techniques. A poly ( -hydroxy ester) based urethane acrylate oligomer was synthesized and a photocurable acrylic based formulation was prepared. Salt particles were introduced to the formulation, which was then poured into cylindrical molds and cured under UV irradiation. Porous scaffolds were obtained after salt leaching. 3T3 cells seeded on the UV cured scaffolds and it was found that cells were well spread on the collagen modified scaffold surface. It can be concluded that the scaffolds provided an effective physical support that allows cell adhesion and proliferation.
引用
收藏
页码：719 / 725
页数：7
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