Intraperitoneal chemotherapy requires expertise and should be the standard of care for optimally surgically resected epithelial ovarian cancer patients

被引:6
|
作者
Walker, J. L. [1 ]
机构
[1] Univ Oklahoma, HSC, Stephensen Canc Ctr, Oklahoma City, OK 73104 USA
关键词
STAGE-III OVARIAN; PRIMARY CYTOREDUCTIVE SURGERY; NEOADJUVANT CHEMOTHERAPY; PROGNOSTIC-FACTORS; PERITONEAL CANCER; CISPLATIN; PACLITAXEL; CARCINOMA; SURVIVAL; TRIAL;
D O I
10.1093/annonc/mdt469
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Women presenting with epithelial ovarian cancer should be treated in centers with both aggressive surgical and chemotherapy teams prepared to confront the modifiable factors, which can optimize the patient's outcome. This implies experience in extensive cytoreductive surgery, including the removal of the tumor from the upper abdomen. An intraperitoneal (IP) catheter should be left in place for the consideration of IP chemotherapy. The supportive care structures need to be in place with teams prepared to help women complete six cycles of intravenous and IP paclitaxel (Taxol) and IP cisplatin with the least toxicity. Survival figures of 128 months are to be expected when no residual disease is left behind and IP chemotherapy is administered successfully.
引用
收藏
页码:41 / 45
页数:5
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