A facile and simple polyaniline-poly(ethylene oxide) based glucose biosensor

被引：24
作者：
Hansen, Betina [1 ]
Hocevar, Marcele A. [1 ]
Ferreira, Carlos A. [1 ]
机构：
[1] Univ Fed Rio Grande do Sul, LAPOL DEMAT, Av Bento Goncalves 9500, BR-91501970 Porto Alegre, RS, Brazil
来源：
SYNTHETIC METALS | 2016年 / 222卷
关键词：
Polyaniline; Poly(ethylene oxide); Nanocomposite; Biosensor; Glucose oxidase; ACID) COMPOSITE FILM; CONDUCTING POLYMER; POLYETHYLENE OXIDE; ELECTROCHEMICAL BIOSENSORS; POLYANILINE NANOCOMPOSITES; CARBON NANOTUBES; IMMOBILIZATION; NANOPARTICLES; NANOFIBERS; FABRICATION;
D O I：
10.1016/j.synthmet.2016.10.028
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
In this work, the fabrication and performance of a simple and efficient glucose biosensor based on chemically synthesized polyaniline-poly(ethylene oxide) nanocomposite (PAni-PEO) have been demonstrated. The nanocomposite was synthesized through rapid-mixing polymerization and characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Fourier transform infrared spectroscopy (FT-IR). The nanocomposite and glucose oxidase (GOx) solutions were placed on a platinum electrode by drop-casting, to produce a glucose biosensor that was characterized by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and chronoamperometry. Under optimal conditions, the biosensor showed a linear range from 1 to 10 mM (R-2 = 0.990) with a high sensitivityof 16.04 mu AmM-1 cm(-2) and a detection limit of 0.82 mM. The interference from ascorbic acid (AA) and uric acid (UA) was also investigated. The results indicated that the biosensor exhibited a satisfactory linear range, sensibility, and selectivity for use as a glucose biosensor, considering the normal range of approximately 4-6 mM of glucose concentration in human blood. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码：224 / 231
页数：8
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