Antifungal drug resistance of pathogenic fungi

被引:357
作者
Kontoyiannis, DP
Lewis, RE
机构
[1] Univ Texas, MD Anderson Canc Ctr, Dept Infect Dis Infect Control & Employee Hlth, Houston, TX 77030 USA
[2] Univ Houston, Coll Pharm, Houston, TX 77030 USA
关键词
D O I
10.1016/S0140-6736(02)08162-X
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Pathogenic fungi have many complex mechanisms of resistance to antifungal drugs. Information about the clinical, cellular, and molecular factors contributing to antifungal-drug resistance continues to accumulate. We critically review the diagnosis, epidemiology, and mechanisms of antifungal drug resistance of pathogenic fungi. Better understanding of this resistance should assist in developing better detection strategies for preventing and treating refractory mycoses In the future.
引用
收藏
页码:1135 / 1144
页数:10
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