Explicit memory training leads to improved memory for face-name pairs in patients with mild cognitive impairment: Results of a pilot investigation

被引:74
作者
Hampstead, Benjamin M. [1 ,2 ]
Sathian, K. [2 ,3 ,4 ]
Moore, Anna Bacon [1 ,2 ]
Nalisnick, Carrie [2 ,3 ]
Stringer, Anthony Y. [1 ,4 ]
机构
[1] Emory Univ, Dept Rehabil Med, Atlanta, GA 30322 USA
[2] Atlanta VAMC, Rehabil R&D Ctr Excellence, Decatur, GA USA
[3] Emory Univ, Dept Neurol, Atlanta, GA 30322 USA
[4] Emory Univ, Dept Psychol, Atlanta, GA 30322 USA
关键词
cognitive rehabilitation; Alzheimer's disease; dementia; aging; associative memory; multi-domain MCI;
D O I
10.1017/S1355617708081009
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Relatively few studies have examined the use of cognitive rehabilitation in patients with mild cognitive impairment (MCI), largely due to the assumption that training will not improve functioning in patients with progressive conditions. Face-name association, an ecologically valid task, is both dependent on the explicit memory system and difficult for MCI patients. During three hour-long sessions, eight patients diagnosed with MCI were trained in the use of explicit memory strategies with 45 face-name pairs. For each pair, they were taught to visually identify a facial feature, link a phonological cue to that feature, and recall the associated name. There was significant improvement in recognition accuracy, along with faster reaction times, for trained face-name pairs. Improved accuracy persisted when tested one month after training. Significant, but less, improvement was also found on untrained stimuli, raising the possibility of generalization of training strategies. preliminary results suggest strategy-based cognitive rehabilitation may be beneficial in patients with MCI, though these results must be replicated with a control group to rule out practice effects.
引用
收藏
页码:883 / 889
页数:7
相关论文
共 25 条
  • [1] Nonpharmacological cognitive interventions in aging and dementia
    Acevedo, Amarilis
    Loewenstein, David A.
    [J]. JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY, 2007, 20 (04) : 239 - 249
  • [2] BACKMAN L, 1991, PSYCHOL AGING, V6, P489
  • [3] Improvement of episodic memory in persons with mild cognitive impairment and healthy older adults:: Evidence from a cognitive intervention program
    Belleville, Sylvie
    Gilbert, Brigitte
    Fontaine, Francine
    Gagnon, Lise
    Menard, Edith
    Gauthier, Serge
    [J]. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 2006, 22 (5-6) : 486 - 499
  • [4] Evidence-based cognitive rehabilitation: Updated review of the literature from 1998 through 2002
    Cicerone, KD
    Dahlberg, C
    Malec, JF
    Langenbahn, DM
    Felicetti, T
    Kneipp, S
    Ellmo, W
    Kalmar, K
    Giacino, JT
    Harley, JP
    Laatsch, L
    Morse, PA
    Catanese, J
    [J]. ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION, 2005, 86 (08): : 1681 - 1692
  • [5] Cognitive training and cognitive rehabilitation for people with early-stage Alzheimer's disease: A review
    Clare, L
    Woods, RT
    [J]. NEUROPSYCHOLOGICAL REHABILITATION, 2004, 14 (04) : 385 - 401
  • [6] Memory rehabilitation in Alzheimer's disease: a review of progress
    De Vreese, LP
    Neri, M
    Fioravanti, M
    Belloi, L
    Zanetti, O
    [J]. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 2001, 16 (08) : 794 - 809
  • [7] Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD
    Dickerson, BC
    Salat, DH
    Greve, DN
    Chua, EF
    Rand-Giovannetti, E
    Rentz, DM
    Bertram, L
    Mullin, K
    Tanzi, RE
    Blacker, D
    Albert, MS
    Sperling, RA
    [J]. NEUROLOGY, 2005, 65 (03) : 404 - 411
  • [8] Reexamining the phonological similarity effect in immediate serial recall: The roles of type of similarity, category cuing, and item recall
    Gupta, P
    Lipinski, J
    Aktunc, E
    [J]. MEMORY & COGNITION, 2005, 33 (06) : 1001 - 1016
  • [9] HAMPSTEAD BM, 2008, FUNCTIONAL NEUROIMAG
  • [10] Jurica P.J., 2001, DEMENTIA RATING SCAL