TRENDS IN NASOPHARYNGEAL CARRIAGE OF STREPTOCOCCUS PNEUMONIAE AMONG CHILDREN ATTENDING DAYCARE CENTERS IN SOUTHEASTERN FRANCE FROM 1999 TO 2006

被引:27
作者
Dunais, Brigitte [1 ]
Bruno, Pascale [2 ]
Carsenti-Dellamonica, Helene
Touboul, Pia [2 ]
Dellamonica, Pierre
Pradier, Christian [2 ]
机构
[1] CHU Nice, Hop Archet 1, Dept Infect Dis, Serv Infectiol, F-06202 Nice, France
[2] CHU Nice, Dept Sante Publ, F-06202 Nice, France
关键词
pneumococcal nasopharyngeal carriage; children's daycare centers; pneumococcal conjugate vaccine; antibiotic use;
D O I
10.1097/INF.0b013e31817bb8cf
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Pneumococcal nasopharyngeal carriage, serotype distribution, and penicillin-susceptibility were monitored among children attending daycare centers in France from 1999 to 2006 to assess the impact of pneumococcal Conjugate vaccine and antibiotic-reducing policies. Pneumococcal carriage remained stable. Immunization rates reached 68% in 2006. Serotype distribution shifted significantly from vaccine serotypes to vaccine-related and nonvaccine serotypes. Antibiotic treatments fell by 50%.
引用
收藏
页码:1033 / 1035
页数:3
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