Dopamine-Melanin Colloidal Nanospheres: An Efficient Near-Infrared Photothermal Therapeutic Agent for In Vivo Cancer Therapy

被引：1825
作者：
Liu, Yanlan [1 ,2 ]
Ai, Kelong [1 ]
Liu, Jianhua [3 ]
Deng, Mo [4 ]
He, Yangyang [5 ]
Lu, Lehui [1 ]
机构：
[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanal Chem, Changchun 130022, Peoples R China
[2] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
[3] Jilin Univ, Hosp 2, Dept Radiol, Changchun 130022, Peoples R China
[4] Jilin Univ, Hosp 2, Dept Clin Lab, Changchun 130022, Peoples R China
[5] Jilin Univ, Hosp 2, Dept Pathol, Changchun 130022, Peoples R China
来源：
ADVANCED MATERIALS | 2013年 / 25卷 / 09期
关键词：
dopamine-melanin; polymers; nanomaterials; biocompatibility; photothermal therapy; PORPHYSOME NANOVESICLES; CONTRAST AGENTS; GOLD NANORODS; ABLATION; CELLS; NANOPARTICLES; LASER; SPECTROSCOPY; HYPERTHERMIA; NANOSHELLS;
D O I：
10.1002/adma.201204683
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new generation of photothermal therapeutic agents based on biopolymer dopamine-melanin colloidal nanospheres is described. Benefitting from their naturally wide distribution in humans, dopamine-melanin colloidal nanospheres exhibit robust biocompatibility and biodegradability, and provide up to 40% photothermal conversion efficiency. After administration, they can efficiently damage tumors at low power density and short irradiation time without damaging healthy tissues. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：1353 / 1359
页数：7
相关论文
共 40 条
[1]   Large-Scale Synthesis of Bi2S3 Nanodots as a Contrast Agent for In Vivo X-ray Computed Tomography Imaging [J].
Ai, Kelong ;
Liu, Yanlan ;
Liu, Jianhua ;
Yuan, Qinghai ;
He, Yangyang ;
Lu, Lehui .
ADVANCED MATERIALS, 2011, 23 (42) :4886-4891
[2]   Theranostic Nanoshells: From Probe Design to Imaging and Treatment of Cancer [J].
Bardhan, Rizia ;
Lal, Surbhi ;
Joshi, Amit ;
Halas, Naomi J. .
ACCOUNTS OF CHEMICAL RESEARCH, 2011, 44 (10) :936-946
[3]   ELECTRON SPIN RESONANCE STUDIES ON MELANIN [J].
BLOIS, MS ;
MALING, JE ;
ZAHLAN, AB .
BIOPHYSICAL JOURNAL, 1964, 4 (06) :471-&
[4]   NADPH oxidases in cardiovascular health and disease [J].
Cave, Alison C. ;
Brewer, Alison C. ;
Narayanapanicker, Anilkumar ;
Ray, Robin ;
Grieve, David J. ;
Walker, Simon ;
Shah, Ajay M. .
ANTIOXIDANTS & REDOX SIGNALING, 2006, 8 (5-6) :691-728
[5]   Surface enhanced Raman scattering (SERS) and FTIR characterization of the sepia melanin pigment used in works of art [J].
Centeno, Silvia A. ;
Shamir, Jacob .
JOURNAL OF MOLECULAR STRUCTURE, 2008, 873 (1-3) :149-159
[6]   Immuno gold nanocages with tailored optical properties for targeted photothermal destruction of cancer cells [J].
Chen, Jingyi ;
Wang, Danling ;
Xi, Jiefeng ;
Au, Leslie ;
Siekkinen, Andy ;
Warsen, Addie ;
Li, Zhi-Yuan ;
Zhang, Hui ;
Xia, Younan ;
Li, Xingde .
NANO LETTERS, 2007, 7 (05) :1318-1322
[7]   Tumor Regression In Vivo by Photothermal Therapy Based on Gold-Nanorod-Loaded, Functional Nanocarriers [J].
Choi, Won Il ;
Kim, Ja-Young ;
Kang, Chul ;
Byeon, Clare C. ;
Kim, Young Ha ;
Tee, Giyoong .
ACS NANO, 2011, 5 (03) :1995-2003
[8]   Facile Synthesis of Monodisperse Superparamagnetic Fe3O4 Core@hybrid@Au Shell Nanocomposite for Bimodal Imaging and Photothermal Therapy [J].
Dong, Wenjie ;
Li, Yongsheng ;
Niu, Dechao ;
Ma, Zhi ;
Gu, Jinlou ;
Chen, Yi ;
Zhao, Wenru ;
Liu, Xiaohang ;
Liu, Changsheng ;
Shi, Jianlin .
ADVANCED MATERIALS, 2011, 23 (45) :5392-5397
[9]   Melanin-like Hydrogels Derived from Gallic Macromers [J].
Fisher, Omar Z. ;
Larson, Benjamin L. ;
Hill, Paulina S. ;
Graupner, David ;
Mai-Thi Nguyen-Kim ;
Kehr, Nermin Seda ;
De Cola, Luisa ;
Langer, Robert ;
Anderson, Daniel G. .
ADVANCED MATERIALS, 2012, 24 (22) :3032-3036
[10]  
Habash Riadh W. Y., 2006, Critical Reviews in Biomedical Engineering, V34, P459, DOI 10.1615/CritRevBiomedEng.v34.i6.20
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