Learning From Trials on Radiation Dose in Non-Small Cell Lung Cancer

被引：2
作者：
Bradley, Jeffrey [1 ]
Hu, Chen [2 ]
机构：
[1] Washington Univ, Sch Med, Dept Radiat Oncol, St Louis, MO USA
[2] Johns Hopkins Univ, Sch Med, Div Oncol, Baltimore, MD USA
来源：
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 2016年 / 96卷 / 04期
关键词：
RADIOTHERAPY; METAANALYSIS; WOMEN;
D O I：
10.1016/j.ijrobp.2016.08.035
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
In this issue of the International Journal of Radiation Oncology . Biology . Physics, Taylor et al present a meta-analysis of published data supporting 2 findings: (1) radiation dose escalation seems to benefit patients who receive radiation alone for non-small cell lung cancer; and (2) radiation dose escalation has a detrimental effect on overall survival in the setting of concurrent chemotherapy. The latter finding is supported by data but has perplexed the oncology community. Perhaps these findings are not perplexing at all. Perhaps it is simply another lesson in the major principle in radiation oncology, to minimize radiation dose to normal tissues. (C) 2016 Elsevier Inc. All rights reserved.
引用
收藏
页码：748 / 750
页数：3
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