Tuberculosis in adulthood The Sk2-Guideline of the German Central Committee against Tuberculosis (DZK) and the German Respiratory Society (DGP) for the diagnosis and treatment of adult tuberculosis patients

被引：18

作者：

Schaberg, Tom ^{[1
]}

Brinkmann, Folke ^{[2
]}

Feiterna-Sperling, Cornelia ^{[3
,4
]}

Geerdes-Fenge, Hilte ^{[5
]}

Hartmann, Pia ^{[6
,7
]}

Haecker, Brit ^{[1
]}

Hauer, Barbara ^{[8
]}

Haas, Walter ^{[8
]}

Heyckendorf, Jan ^{[9
]}

Lange, Christoph ^{[10
,11
,12
,13
,14
]}

Maurer, Florian P. P. ^{[15
,16
]}

Nienhaus, Albert ^{[17
]}

Otto-Knapp, Ralf ^{[1
]}

Priwitzer, Martin ^{[18
]}

Richter, Elvira ^{[19
]}

Salzer, Helmut J. F. ^{[20
]}

Schoch, Otto ^{[21
]}

Schoenfeld, Nicolas

Stahlmann, Ralf

Bauer, Torsten ^{[1
]}

机构：

[1] Deutsch Zentralkomitee Bekampfung TB eV? DZK, Walterhoferstr 11, Haus Q, D-14165 Berlin, Germany

[2] Ruhr Univ Bochum, Univ Kinderklin, Abt Padiatr Pneumol CF Zentrum, Bochum, Germany

[3] Charite Univ Med Berlin, Freie Univ Berlin, Klin Padiatr Schwerpunkt Pneumol Immunol & Intensi, Berlin, Germany

[4] Humboldt Univ, Berlin, Germany

[5] Univ Med Rostock, Zent Innere Med, Rostock, Germany

[6] Lab Dr Wisplinghoff Koln, Klin Infektiol, Cologne, Germany

[7] St Vinzenz Hosp, Dept Klin Infektiol, Cologne, Germany

[8] Robert Koch Inst, Berlin, Germany

[9] Univ Klinikum Schleswig Holstein, Klin Innere Med I, Campus Kiel, Kiel, Germany

[10] Forschungszentrum Borstel, Klin Infektiol, Sulfeld, Germany

[11] Deutsch Zent Infekt Forsch DZIF, Standort Hamburg Lubeck Borstel Riems, Braunschweig, Germany

[12] Univ Lubeck, Resp Med & Int Hlth, Lubeck, Germany

[13] Baylor Coll Med, Houston, TX USA

[14] Texas Children's Hosp, Global TB Program, Houston, TX USA

[15] Forschungszentrum Borstel, Natl Referenzzent Mykobakterien, Borstel, Germany

[16] Univ Klinikum Hamburg Eppendorf, Inst Med Mikrobiol & Virol Hyg, Hamburg, Germany

[17] Univ Klinikum Hamburg Eppendorf UKE, Inst Versorgungsforsch Dermatol & Pflegeberufen IV, Hamburg, Germany

[18] Gesundheitsamt, Stuttgart, Germany

[19] MVZ Lab Dr Limbach & Kollegen GbR, Heidelberg, Germany

[20] Kepler Univ Klinikum, Linz, Austria

[21] Kantonsspital St Gallen, St Gallen, Switzerland

来源：

PNEUMOLOGIE | 2022年 / 76卷 / 11期

关键词：

MULTIDRUG-RESISTANT TUBERCULOSIS; HIV-INFECTED ADULTS; MEROPENEM/CLAVULANATE-CONTAINING REGIMENS; ISONIAZID PREVENTIVE THERAPY; GAMMA RELEASE ASSAYS; INDUCED LIVER-INJURY; OF-THE-ART; LATENT TUBERCULOSIS; ANTIRETROVIRAL THERAPY; DRUG-RESISTANT;

D O I：

10.1055/a-1934-8303

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

In Germany tuberculosis is a rare disease and usually well treatable. Worldwide it is one of the most common infectious diseases with approximately 10 million new cases every year.Even with low incidences in Germany, tuberculosis is an important differential diagnosis especially due to international developments and migration movements. With a decreasing experience there's a continuous demand on accurate and up-to-date information. This guideline covers all aspects of microbiological diagnostics, basic principles of standard therapy, treatment of extrapulmonary tuberculosis, management of side effects, special features of diagnosis and treatment of resistant tuberculosis, and treatment in TB-HIV coinfection. Also, it explains when treatment in specialized centers is required, aspects of care and legal regulations and the diagnosis and preventive therapy of latent tuberculosis infection.The update of the S2k guideline "Tuberculosis in Adults " is intended to serve as a guideline for prevention, diagnosis, and treatment of tuberculosis for all those involved in tuberculosis care and to help meet the current challenges in dealing with tuberculosis in Germany.

引用

页码：727 / 819

页数：93

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